MedTrace Logo

Serpentine vs Traditional Hydrophilic Guidewire Tracking in Complex Radial Anatomy

NCT07707427 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 204

Last updated 2026-07-16

No results posted yet for this study

Summary

Coronary angiography and angioplasty are commonly performed through the radial artery. In some patients, anatomical variations of the radial and brachial arteries, such as loops, increased tortuosity or sharp angulations may pose challenges to equipment advancement.

Both the hydrophilic guidewire 0,035'' approach and the "Serpentine" technique have been described in the literature as techniques for overcoming radial anatomical challenges, with the hydrophilic guidewire approach being the more commonly used method.

In practical terms, both techniques involve the use of the same standard materials, with differences relating mainly to operator handling and technical manipulation. This study does not introduce any experimental device, material, or treatment; instead, it aims to compare the established approach using a 0.035'' hydrophilic guidewire with the emerging " Serpentine" technique with respect to effectiveness, procedural time, and safety.

Conditions

  • Transradial Access(TRA)
  • Coronary Angiography (CAG)
  • Percutaneous Coronary Intervention (PCI)
  • Radial Artery Loop
  • Radial Artery Tortuosity
  • Serpentine Technique
  • Hydrophilic Guidewire
  • Complex Radial Anatomy
  • Vascular Complications
  • Coronary Catheterization

Interventions

PROCEDURE

Serpentine Technique

Catheter-based navigation technique using controlled rotational catheter manipulation to cross radial or brachial artery loops, tortuosity, or sharp angulation during transradial coronary angiography or PCI.

PROCEDURE

Hydrophilic Technique

Navigation of radial or brachial artery loops, tortuosity, or sharp angulation using a 0.035-inch hydrophilic guidewire during transradial coronary angiography or PCI.

Sponsors & Collaborators

  • University Hospital of Patras

    lead OTHER

Principal Investigators

  • Grigorios Tsigkas, MD, PhD · University Hospital of Patras

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-14
Primary Completion
2029-05-31
Completion
2029-11-30

Countries

  • Greece

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07707427 on ClinicalTrials.gov