Uncertainty About the Benefits of New Cancer Drugs and Patients' Treatment Preferences
NCT07694310 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3000
Last updated 2026-08-04
Summary
This study of current or former cancer patients will evaluate the effect of learning about uncertainties with the benefits of a new cancer drug on their hypothetical decisions to take the drug and their perceptions of the drug's effectiveness.
Conditions
Interventions
- OTHER
-
Control
No uncertainty information
- OTHER
-
Unvalidates surrogate endpoint
Zenova has only been shown to shrink the size of tumors. It is unknown whether Zenova improves how patients feel or how long they live.
- OTHER
-
Limited study population
Zenova has not been studied in patients similar to Alex (patients with her race and ethnicity). It is unknown whether Zenova will work and what harms it will have for patients like her.
- OTHER
-
Small magnitude of effect
It is unknown whether patients with non-small cell lung cancer will notice an improvement with Zenova.
- OTHER
-
Multiple uncertainties
All 3 statements shown above
Sponsors & Collaborators
-
Harvard Medical School and Harvard Pilgrim Health Care Institute
collaborator UNKNOWN -
London School of Economics and Political Science
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-07-14
- Primary Completion
- 2026-10-01
- Completion
- 2026-10-01
More Related Trials
-
An Evaluation of the Psychological Impact of Early Phase Clinical Trials in Cancer Patients.
NCT03818230 ·Status: COMPLETED
-
Assessment of Patient Experience During Treatment for Cancer
NCT01553825 ·Status: COMPLETED
-
The Role of Emotions and Regulatory Focus in Decision Making That Involves Risk Tradeoffs
NCT02874053 ·Status: WITHDRAWN
-
Treatment Decision Making Between Oncologists and Women With Newly Diagnosed Breast Cancer and Their Healthy Companions
NCT00891969 ·Status: TERMINATED
-
Facilitating Web-based Patient Decision Support: Decision About Medication to Lower Breast Cancer Risk
NCT00906321 ·Status: COMPLETED ·Phase: NA
-
Transitoriness in Cancer Patients, Psychosocial Issues in Cancer Care
NCT00364078 ·Status: COMPLETED
-
Study of Decision Making in Patients Participating in Phase I Clinical Trials
NCT00054223 ·Status: COMPLETED ·Phase: NA
-
Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
NCT00770419 ·Status: WITHDRAWN
-
Evidence Based Information Provision to Improve Decision Making After Oesophagogastric Cancer Diagnosis (SOURCE)
NCT04232735 ·Status: UNKNOWN ·Phase: NA
-
Training in Evidence-based Treatments in Psycho-Oncology
NCT05674357 ·Status: RECRUITING ·Phase: NA
-
What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials
NCT06326242 ·Status: RECRUITING
-
Mind Programme for Women With Breast Cancer (Nationwide Coverage)
NCT06212414 ·Status: RECRUITING ·Phase: NA
-
Acceptance and Commitment Therapy (ACT) - Based Treatment Development for Cancer Patients Treated for Pain
NCT03910296 ·Status: COMPLETED
-
A ProspectiveTrial Using Video Images in Advance Care Planning in Hospitalized Seriously Ill Patients With Advanced Cancer
NCT01527331 ·Status: UNKNOWN ·Phase: NA
-
Factors Influencing Decision-Making About the Use of Chemoprevention in Women at Increased Risk for Breast Cancer
NCT01399359 ·Status: COMPLETED
-
Side Effect Prevention Training (SEPT) for Nocebo Effects in Breast Cancer Patients
NCT01741883 ·Status: UNKNOWN ·Phase: NA
-
Evidence Development in Cancer Treatment - Real World: PREDiCTrw
NCT06242912 ·Status: RECRUITING ·Phase: NA
-
A Therapy Intervention to Address Fear of Recurrence in Men and Women With Cancer
NCT02382315 ·Status: COMPLETED ·Phase: NA
-
Avoiding Low-value Treatments in Older Women With Early-stage Breast Cancer: Piloting a Patient Decision Aid
NCT05140252 ·Status: COMPLETED ·Phase: NA
-
A Novel Intervention for Patients With Cancer
NCT05643027 ·Status: COMPLETED ·Phase: NA
-
Oral Therapies in Oncology: Cognitive Function and Compliance
NCT01597284 ·Status: TERMINATED
-
CAncer, NUtrition and Taste 2
NCT05027490 ·Status: COMPLETED ·Phase: NA
-
Food-related Quality of Life in Patients With Cancer
NCT07437326 ·Status: NOT_YET_RECRUITING
-
Perception Prognosis, Goals of Treatment, and Communication
NCT01401894 ·Status: COMPLETED
-
Evaluation of a Mobile App Program for Coping With Cancer
NCT06923501 ·Status: RECRUITING ·Phase: NA