MedTrace Logo

Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management

NCT07683650 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2026-07-14

No results posted yet for this study

Summary

The aim of this study is to evaluate the efficacy of hyaluronic acid and I-PRF mixture for intra-articular injection following arthrocentesis in the management of TMJ reducible disc displacement.

Conditions

  • TMJ Disc Displacement With Reduction

Interventions

PROCEDURE

18 joints that receive arthrocentesis using 100 ml of ringer lactate solution

18 joints that receive arthrocentesis using 100 ml of ringer lactate solution

PROCEDURE

Arthrocentesis followed by hyaluronic acid injection

18 joints that receive arthrocentesis using 100 ml of ringer lactate solution followed by intra-articular injection of 1 ml of hyaluronic acid

PROCEDURE

Arthrocentesis followed by injection of hyaluronic acid and betamethasone mixture

18 joints that receive arthrocentesis using 100 ml of ringer lactate solution followed by intra-articular injection of hyaluronic acid and betamethasone mixture

PROCEDURE

Arthrocentesis followed by injection of hyaluronic acid and I-PRF mixture

18 joints that receive arthrocentesis using 100 ml of ringer lactate solution followed by intra-articular injection of hyaluronic acid and I-PRF mixture

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Nada Hamed · Faculty of Dentistry Mansoura University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-06
Primary Completion
2026-12-31
Completion
2027-02-28

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07683650 on ClinicalTrials.gov