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Retrospective Observational Multicenter Study on the Treatment Patterns, Extra-Intestinal Manifestations, Resource Utilisation, and Outcomes of Patients With Inflammatory Bowel Disease in Dutch Hospitals

NCT07682038 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 3500

Last updated 2026-07-02

No results posted yet for this study

Summary

This multicenter retrospective real-world data study will evaluate the treatment pathways and disease burden of adult patients with Crohn's disease (CD) and ulcerative colitis (UC) treated in 5-10 Dutch hospitals between 2018 and 2026.

The study will assess:

* Treatment sequences, switching patterns, and treatment duration
* Prevalence and incidence of extra-intestinal manifestations (EIMs)
* Healthcare resource utilization (hospitalizations, outpatient visits, endoscopies, surgery, and length of stay)
* Direct healthcare costs
* Availability of disease activity biomarkers

Using linked administrative, prescription, procedure, and laboratory data, outcomes will be analyzed by age, line of therapy, and clinical characteristics. Special focus will be placed on the impact of EIMs on treatment patterns, healthcare utilization, and costs.

The findings will provide real-world evidence on IBD management in the Netherlands and support clinical decision-making, healthcare planning, and future research on treatment optimization and coexisting immune-mediated conditions.

Conditions

  • Crohn Disease
  • Inflammatory Bowel Disease (IBD)
  • Colitis Ulcerative

Interventions

OTHER

Routine hospital care data (observational)

This is a non-interventional, retrospective observational study. No intervention is administered as part of this study. The study observes and analyses routinely collected hospital data on existing treatment patterns for Crohn's disease and ulcerative colitis, including conventional therapies and advanced systemic treatments (biologics, JAK inhibitors, S1P modulators), as prescribed in routine clinical care.

Sponsors & Collaborators

  • LOGEX

    lead INDUSTRY

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-01
Primary Completion
2027-03-31
Completion
2027-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07682038 on ClinicalTrials.gov