A Real World Study of Participants With Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor Mutation (EGFRm)
NCT07680907 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 250
Last updated 2026-08-03
Summary
This study aims to better understand people who have advanced or metastatic non-small cell lung cancer (NSCLC) with an EGFR mutation. NSCLC is an advanced stage cancer of the lung, occurring due to mutations (changes) in the EGFR gene. The study will assess the participant demographic background (that is age, gender etc.), the treatments they receive, how well those treatments work, and their health outcomes.
Conditions
- Carcinoma, Non-Small-Cell Lung
Sponsors & Collaborators
-
Janssen-Cilag Farmaceutica Ltda.
lead INDUSTRY
Principal Investigators
-
Janssen-Cilag Farmaceutica, Lda. Clinical Trial · Janssen-Cilag Farmaceutica, Lda.
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-09-30
- Primary Completion
- 2026-11-30
- Completion
- 2026-11-30
More Related Trials
-
Epidermal Growth Factor Receptor and K-ras Mutations in Patients With Stage III Non-Small Cell Lung Cancer
NCT00898924 ·Status: COMPLETED
-
Genomic Landscape of EGFR Mutant NSCLC Prior to Erlotinib and at the Time of Disease Progression
NCT02431169 ·Status: TERMINATED
-
Erlotinib in Patients With Resected, Early Stage NSCLC With Confirmed Mutations in the EGFR
NCT00567359 ·Status: COMPLETED ·Phase: PHASE2
-
Retrospective Study in Non Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR)
NCT02293733 ·Status: COMPLETED
-
A Study For Patients With EGFRm (Epidermal Growth Factor Receptor Mutant) Lung Cancer
NCT02297425 ·Status: WITHDRAWN ·Phase: PHASE2
-
Expanded Access Study of Afatinib in Treatment-naive or Chemotherapy Pre-treated Patients With Non-small Cell Lung Cancer (NSCLC)
NCT01931306 ·Status: APPROVED_FOR_MARKETING
-
A Phase I/II, Multicenter, Open-label Study of EGFRmut-TKI EGF816, Administered Orally in Adult Patients With EGFRmut Solid Malignancies
NCT02108964 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Mutations in the Epidermal Growth Factor Receptor(EGFR) Gene in Non-Small Cell Lung Carcinoma (NSCLC) and the Relation to Response of Treatment With Erlotinib
NCT00815971 ·Status: UNKNOWN
-
Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib
NCT02759835 ·Status: COMPLETED ·Phase: PHASE2
-
A Chart Review Study of Adults With Advanced NSCLC
NCT05207423 ·Status: COMPLETED
-
PRe-Operative Gefitinib in Resectable EGFR Mutation Positive Lung Cancer With Sector Sequencing for Biomarker Discovery
NCT02804776 ·Status: COMPLETED ·Phase: PHASE2
-
Resistance & Activating Mutations Diagnosed Among NSCLC Community Dwelling EGFR Mutation Positive Patients
NCT03137264 ·Status: COMPLETED
-
Epidemiological Study to Evaluate the Prevalence of Epidermal Growth Factor Receptor (EGFR) Mutation Status in Patients With Newly Diagnosed Locally Advanced or Metastatic Non Small Cell Lung Cancer (NSCLC)
NCT01081496 ·Status: COMPLETED
-
Real-World Outcomes of Resected EGFR-Mutated NSCLC Patients Treated With Adjuvant EGFR-TKI in China
NCT07593248 ·Status: RECRUITING
-
Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC
NCT06376084 ·Status: ACTIVE_NOT_RECRUITING
-
Local Therapies for Oligometastatic Non-Small Cell Lung Cancer Harboring Sensitizing EGFR Mutations
NCT02450591 ·Status: COMPLETED ·Phase: NA
-
A Study Osimertinib in Patients With Stage 4 Non-small Cell Lung Cancer With Uncommon EGFR Mutations
NCT03434418 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Erlotinib for Operable Stage II or IIIA NSCLC With EGFR Mutations
NCT01470716 ·Status: UNKNOWN ·Phase: PHASE2
-
Diagnosis and Treatment Strategies in Patients With NSCLC With or Without EGFR Mutations.
NCT01525199 ·Status: COMPLETED
-
Evaluation in Real World of Molecular Testing and Treatment Patterns for EGFR Mutation in Lung Cancer Patients
NCT03721289 ·Status: COMPLETED
-
Observational Multicenter Study in Patients Receiving Chemotherapy and Amivantamab for Metastatic Non-small Cell Lung Cancer
NCT07563205 ·Status: RECRUITING
-
A Retrospective Study About Treatment Strategy After First/Second Line EGFR-TKI Failure
NCT02618590 ·Status: UNKNOWN
-
EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study
NCT06486142 ·Status: RECRUITING ·Phase: PHASE3
-
Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complex
NCT02876081 ·Status: WITHDRAWN ·Phase: PHASE2
-
Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3)
NCT02695290 ·Status: TERMINATED ·Phase: PHASE4