Evaluation in Real World of Molecular Testing and Treatment Patterns for EGFR Mutation in Lung Cancer Patients
NCT03721289 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 463
Last updated 2019-06-12
Summary
Evaluate molecular testing and treatment patterns for EGFR mutation in two different cohorts of stage IV NSCLC, at diagnosis (treatment naïve) and at the moment of progression to EGFR-TKIs. This study is non-indication seeking (NIS), descriptive in nature and does not attempt to test any specific a priori hypotheses.
Conditions
- Carcinoma, Non-Small-Cell Lung
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Florencia Reinhold, MD · AstraZeneca
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-11-29
- Primary Completion
- 2019-03-09
- Completion
- 2019-03-09
Countries
- Argentina
- Chile
- Colombia
- Uruguay
Study Locations
More Related Trials
-
Retrospective Study in a NSCLC M+ p
NCT01795352 ·Status: COMPLETED
-
EGFR-TKI Resistance Profile in Chinese Patients With Advanced EGFRm+ NSCLC
NCT02988141 ·Status: UNKNOWN
-
Observational Study to Characterize the Incidence of EGFR Mutation Positive and Advanced NSCLC Patients
NCT01717105 ·Status: UNKNOWN
-
Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced NSCLC Patients
NCT04912687 ·Status: COMPLETED ·Phase: NA
-
Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm
NCT05546866 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Resistance & Activating Mutations Diagnosed Among NSCLC Community Dwelling EGFR Mutation Positive Patients
NCT03137264 ·Status: COMPLETED
-
Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC
NCT04324164 ·Status: RECRUITING
-
Retrospective Study in Non Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR)
NCT02293733 ·Status: COMPLETED
-
Study in NSCLC: is Timely Analysis of EGFR-mutation Status Feasible in Region Antwerp, Belgium.
NCT01260038 ·Status: COMPLETED
-
STUDY OBSERVATIONAL OF ERLOTINIB AS SECOND LINE TREATMENT IN PATIENTS WITH SQUAMOUS NSCLC AND EGFR NATIVE
NCT02328391 ·Status: UNKNOWN
-
A Multicenter Randomized Phase III Study Comparing Second-line Treatment With Chemotherapy Associated or Not to Erlotinib in NSCLC Patients With Secondary Resistance to TKI-EGFR
NCT02178397 ·Status: TERMINATED ·Phase: PHASE3
-
Phase II AZD9291 Open Label Study in NSCLC After Previous EGFR TKI Therapy in EGFR and T790M Mutation Positive Tumours
NCT02094261 ·Status: COMPLETED ·Phase: PHASE2
-
Identification of EGFR-TKIs Sensitivity or Resistance Markers in NSCLC May Help in Optimal Patient Selection
NCT00831454 ·Status: COMPLETED
-
A Study to Assess the Incidence of EGFR Mutation in Patients With Newly Diagnosed Locally Advanced or Metastatic Non-Small Cell Lung Cancer in the UK, And of Tarceva (Erlotinib) as First-Line Therapy in EGFR Mutation Positive Patients.
NCT01250119 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment Patterns, Outcomes and Testing in EGFRm NSCLC Patients With EGFR TKI 1L Across Europe (REFLECT)
NCT04031898 ·Status: COMPLETED
-
PRe-Operative Gefitinib in Resectable EGFR Mutation Positive Lung Cancer With Sector Sequencing for Biomarker Discovery
NCT02804776 ·Status: COMPLETED ·Phase: PHASE2
-
Epidemiological and Scientific Evaluation of EGFR Mutation Status in Patients With Newly Diagnosed Locally Advanced or m
NCT00997230 ·Status: COMPLETED
-
Observational Study on the Management of Patients With Non Small Cell Lung Cancer Adenocarcinoma
NCT01167972 ·Status: COMPLETED
-
A Retrospective Study About Treatment Strategy After First/Second Line EGFR-TKI Failure
NCT02618590 ·Status: UNKNOWN
-
Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed.
NCT04737382 ·Status: RECRUITING ·Phase: NA
-
EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study
NCT06486142 ·Status: RECRUITING ·Phase: PHASE3
-
A Study to Predict Gefitinib' s Efficacy for Lung Cancer by Plasma Free Nucleic Acids EGFR Gene Mutation Test
NCT02738684 ·Status: UNKNOWN
-
Erlotinib Treatment Beyond Progression in EGFR Mutant NSCLC
NCT02064491 ·Status: COMPLETED ·Phase: PHASE2
-
A Retrospective EGFR Mutation Status Study in Chinese NSCLC Patients Using Paired Plasma and Tissue Samples
NCT01382992 ·Status: UNKNOWN
-
Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer
NCT02228369 ·Status: COMPLETED ·Phase: PHASE1