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Vertical Facial Morphology and Occlusal Force Changes After Masseter Botulinum Toxin Injection in Bruxism

NCT07673471 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-06-29

No results posted yet for this study

Summary

This study investigated whether the shape of the face affects how jaw muscles respond to botulinum toxin injections in people who grind their teeth (bruxism). Participants were divided into two groups based on their facial structure: low-angle (shorter face height) and normal-angle. Each participant received botulinum toxin type A injections into the masseter (jaw) muscle. Bite force measurements were taken before and 15 days after the injection using the T-Scan computerized occlusal analysis system. The study aimed to determine whether facial structure influences the early changes in bite force balance following the injection.

Conditions

  • Bruxism
  • Occlusal Changes

Interventions

BIOLOGICAL

Botulinum Toxin Type A (BOTOX) Injection

Botulinum toxin type A (Botox®, Allergan, Irvine, CA, USA) was injected bilaterally into the masseter muscle at a dose of 25 units per side (50 units total per patient). Injections were performed by a single experienced clinician under sterile conditions using a 30-gauge needle.

Sponsors & Collaborators

  • Biruni University

    lead OTHER

Principal Investigators

  • Esra Agaoğlu Mogul · Department of Orthodontics, Faculty of Dentistry, Biruni University

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-09
Primary Completion
2026-05-08
Completion
2026-05-08

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07673471 on ClinicalTrials.gov