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Sevoflurane Versus Propofol for Laryngeal Mask Airway Placement in Children Undergoing Surgery

NCT07673003 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 170

Last updated 2026-06-29

No results posted yet for this study

Summary

The goal of this clinical trial is to compare two commonly used anesthetic medicines, sevoflurane and propofol, for inserting a laryngeal mask airway (LMA) in children undergoing minor elective surgery. A laryngeal mask airway is a device placed in the throat to help children breathe safely during anesthesia.

The main questions this study aims to answer are:

* Does sevoflurane produce a faster onset of anesthesia than propofol?
* Is there a difference between sevoflurane and propofol in the time required to achieve jaw relaxation for LMA insertion?
* Is there a difference between the two medicines in the time required for successful LMA insertion?

The researchers hypothesize that children receiving sevoflurane will have a shorter induction time than those receiving propofol.

A total of 170 children aged 4 to 12 years who are undergoing minor surgical procedures below the umbilicus will participate in the study. Participants will be randomly assigned to receive either intravenous propofol or inhaled sevoflurane for induction of anesthesia.

During the procedure, the anesthesia team will measure the time taken to lose consciousness, the time required to achieve adequate jaw relaxation, and the time needed for successful insertion of the laryngeal mask airway. These measurements will help determine which anesthetic agent provides better conditions for LMA insertion in children.

Conditions

  • General Anaesthesia
  • Airway Devices
  • Airway Control

Interventions

DRUG

propofol

Intravenous propofol 3 mg/kg bolus will be administered for induction of general anesthesia before LMA insertion in pediatric patients.

DRUG

Sevoflurane

Sevoflurane 7% will be delivered via inhalation in a nitrous oxide/oxygen mixture (2:1) for induction of general anesthesia prior to LMA insertion in pediatric patients.

Sponsors & Collaborators

  • Children's Hospital and Institute of Child Health, Multan

    lead OTHER_GOV

Principal Investigators

  • Syed S Abbas, FCPS · Children's Hospital and Institute of Child Health, Multan

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
4 Years
Max Age
12 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-01
Primary Completion
2025-11-30
Completion
2025-11-30

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07673003 on ClinicalTrials.gov