MedTrace Logo

Comparative Evaluation of the Efficacy of Letrozole, L-Carnitine, and Their Combination on Sperm Quality, Oxidative Stress, and ART Outcomes in Men With Idiopathic Oligoasthenoteratozoospermia.

NCT07669402 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-06-30

No results posted yet for this study

Summary

This is a randomized clinical trial evaluating the efficacy of Letrozole, L-Carnitine, and their combination on sperm quality, oxidative stress, and ART outcomes in men with idiopathic oligoasthenoteratozoospermia.

Conditions

  • Idiopathic Oligoasthenoteratozoospermia
  • Male Infertility

Interventions

DRUG

Letrozole 2.5mg

Letrozole 2.5 mg tablet administered orally once daily for 3 months.

DRUG

L-carnitine

L-Carnitine 1000 mg capsule administered orally once daily for 3 months.

Sponsors & Collaborators

  • Tehran University of Medical Sciences

    lead OTHER

Principal Investigators

  • Azim Hedayatpour, Professor, PhD · Tehran University of Medical Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-12-01
Primary Completion
2026-02-28
Completion
2026-03-31

Countries

  • Iran

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07669402 on ClinicalTrials.gov