Analysis of Efficacy and Outcomes of Immunotherapy for Malignant Tumors: A Prospective Non-interventional Clinical Study
NCT07665697 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2026-06-24
Summary
The population receiving immunotherapy is heterogeneous. Multiple factors, including combination treatment modalities, influence the immune response, and survival outcomes also vary among individuals receiving immunotherapy. The aim of this study is to develop and validate a clinical prediction model that can predict survival outcomes of immunotherapy for malignant tumors, and to assess the calibration and discrimination of this model in a prospective independent cohort.
Conditions
- Neoplasms
- Drug Therapy
- Immune Checkpoint Inhibitors (ICIs)
Sponsors & Collaborators
-
Sichuan University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-30
- Primary Completion
- 2029-06-15
- Completion
- 2029-06-15
Countries
- China
Study Locations
More Related Trials
-
Identification and Evaluation of Circulating Tumor Cells and Tumor Related Rare Cells in Immunotherapy
NCT03434912 ·Status: UNKNOWN
-
Immune-Related Adverse Events and Associated Biomarkers in Patients Receiving Cancer Immunotherapy
NCT06089967 ·Status: COMPLETED
-
NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts
NCT04960059 ·Status: COMPLETED
-
A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
NCT04794972 ·Status: RECRUITING ·Phase: PHASE1
-
Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor
NCT03662815 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy
NCT02661659 ·Status: WITHDRAWN ·Phase: PHASE1
-
Immunotherapy Using Precision T Cells Specific to Personalized Neo-antigen for the Treatment of Advanced Malignant Tumor of Biliary Tract
NCT02632019 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Selecting Patients Who May Benefit From Immunotherapy by Tissue-based Biomarkers.
NCT05593419 ·Status: RECRUITING
-
Immunotherapy in MSI/dMMR Tumors in Perioperative Setting.
NCT04795661 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET)
NCT06900296 ·Status: NOT_YET_RECRUITING
-
A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors
NCT06716619 ·Status: RECRUITING ·Phase: PHASE1
-
NK Cell-based Immunotherapy as Maintenance Therapy for Small-Cell Lung Cancer.
NCT03410368 ·Status: UNKNOWN ·Phase: PHASE2
-
Neo-adjuvant Immunotherapy Master Trial for Localized Cancers
NCT07262489 ·Status: RECRUITING ·Phase: PHASE2
-
Personalized Vaccine for Cancer Immunotherapy
NCT04879888 ·Status: COMPLETED ·Phase: PHASE1
-
The Predicted Potential of Quantitative T Cell Repertoire(TCR) in Anti-PD-L1 Treatment in NSCLC Patients
NCT03228368 ·Status: UNKNOWN
-
A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Solid Tumors
NCT05039931 ·Status: WITHDRAWN ·Phase: PHASE1
-
Comparison of Autogenic and Allogenic NK Immunotherapy on the Outcome of Recurrent Solid Tumors
NCT02853903 ·Status: COMPLETED ·Phase: PHASE2
-
Development of a New Immunotherapy Using Intramuscular Administration of Autologous Total IgG
NCT03695757 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Clinical Efficacy and Safety of NK and NKT Cells Infusion in Patients With Non Small Cell Lung Cancer
NCT03198923 ·Status: UNKNOWN ·Phase: PHASE1
-
IL-15 Enhanced NK Cell Therapy for Solid Tumors
NCT07621471 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Oral Pooled Fecal Microbiotherapy (MaaT033) Concomitant to Cemiplimab Versus Best Investigator's Choice in Patients With Resistance to Treatment Due to Antibiotics Uptake With Advanced Non-small Cell Lung Cancer
NCT07001618 ·Status: RECRUITING ·Phase: PHASE2
-
Autologous Natural Killer T Cells Infusion for the Treatment of Cancer
NCT01801852 ·Status: UNKNOWN ·Phase: NA
-
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
NCT04242095 ·Status: RECRUITING
-
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
NCT04871542 ·Status: RECRUITING
-
ImmuniCell® in Patients With Advanced Cancers
NCT02459067 ·Status: TERMINATED ·Phase: PHASE2