Apheresis Collection for New Drug Development and Evaluation Research
NCT07663565 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2026-06-23
Summary
Peripheral Blood Mononuclear Cells (PBMC) are a mixed population of cells with a single nucleus found in peripheral blood (i.e., blood outside the bone marrow), including natural killer cells (NK), T lymphocytes (70% - 90%), and B lymphocytes. They can be further isolated and purified and are the main source of immune cells. This study will be conducted at our hospital, with a planned recruitment of 200 subjects. Subjects who meet the inclusion criteria and do not meet the exclusion criteria will have their peripheral blood mononuclear cells collected via apheresis. Each subject will need to provide an apheresis sample containing approximately 8×10\^9 mononuclear cells (with a sample volume of about 150 mL).
Conditions
- PBMCs
Interventions
- OTHER
-
None AHT
No intervention measures
Sponsors & Collaborators
-
TCRx Therapeutics Co.Ltd
lead INDUSTRY
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-06-22
- Primary Completion
- 2028-06-21
- Completion
- 2028-12-31
Countries
- China
Study Locations
More Related Trials
-
Switched Memory B-cells as a Marker for Humoral Immune System Recovery in Patients With Secondary Antibody Deficiency Due to Hematological Malignancies
NCT05612607 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Response to Extracorporeal Photo-aphereSiS
NCT07316829 ·Status: ACTIVE_NOT_RECRUITING
-
Evaluation of the Safety of Cytokine-Induced-Killer Cells During Early Transplant Period of Autologous Hematopoietic Stem Cell Transplant Recipients.
NCT07692607 ·Status: COMPLETED ·Phase: NA
-
Autologous Tolerogenic Dendritic Cells (ATDC) for Highly Sensitized Kidney Transplant Recipients
NCT06852625 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device
NCT01210716 ·Status: COMPLETED ·Phase: PHASE3
-
Peripheral Blood Lymphocyte Therapy to Prevent Lymphoproliferative Disorders Caused by Epstein-Barr Virus in Patients Who Have Undergone Transplantation
NCT00005606 ·Status: COMPLETED ·Phase: PHASE2
-
T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation
NCT03180216 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Individualized Application of Anti-Thymocyte Globulin(ATG)in Unrelated Donor Hematopoietic Stem Cell Transplantation
NCT07648992 ·Status: RECRUITING ·Phase: PHASE4
-
The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT
NCT06362967 ·Status: RECRUITING ·Phase: PHASE2
-
Biological Therapy in Treating Patients at High-Risk or With Lymphoma, Lymphoproliferative Disease, or Malignancies
NCT00002663 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Pneumonia Vaccine in Bone Marrow Transplant Recipients: Usefulness of Donor Vaccination
NCT00143780 ·Status: COMPLETED ·Phase: PHASE4
-
Manufacture of Clinical T-cell Products for Future Treatment
NCT05713513 ·Status: COMPLETED
-
BioRBC Survival in Adults With Prior Antibody Response to BioRBCs
NCT02077751 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluate Effects and Safety of Pre-load Myfortic® in Transplant Patients
NCT01336296 ·Status: COMPLETED ·Phase: PHASE4
-
Generation of SARS-CoV-2-specific T Lymphocytes From Recovered Donors and Administration to High-risk COVID-19 Patients
NCT05447013 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation
NCT03378102 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients
NCT00189761 ·Status: COMPLETED ·Phase: PHASE2
-
Exploration of Adaptive Antitumoral Immune Cells Through Lymphapheresis in Cancer Patients : ALCYTA
NCT05354765 ·Status: RECRUITING ·Phase: NA
-
Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT
NCT06119256 ·Status: RECRUITING ·Phase: PHASE1
-
EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection
NCT03266653 ·Status: RECRUITING ·Phase: PHASE2
-
Unrelated Cord Blood Transplantation for EBV-associated Lymphoproliferative Disorders
NCT07381738 ·Status: RECRUITING ·Phase: PHASE2
-
Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T Cells in Patients With Severe COVID-19
NCT04351659 ·Status: UNKNOWN
-
CD45RA-depleted DLI for the Prevention of Viral Infections in High-risk Patients After Haploidentical Transplantation
NCT07672964 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients
NCT04723706 ·Status: COMPLETED
-
Identification and Analysis of Immunomodulatory Molecules in Patients With Hematologic Disorders and Healthy Volunteers
NCT00223483 ·Status: COMPLETED