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Effect of Pre-exercise Inhalation of Molecular Hydrogen on Metabolic Response During Graded Exercise in Healthy Women

NCT07644000 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2026-06-25

No results posted yet for this study

Summary

The goal of this clinical trial is to evaluate if molecular hydrogen can reduce the metabolic response during graded exercise in healthy women aged 18-30 years. The main questions it aims to answer are:

* Does molecular hydrogen reduce the respiratory exchange ratio?
* Does molecular hydrogen reduce oxygen uptake?

Researchers will compare molecular hydrogen to a placebo (ambient air containing no molecular hydrogen) to see if molecular hydrogen reduces the metabolic response.

Participants will:

* Inhale molecular hydrogen for 60 minutes each day for 7 days.
* Undergo an exercise testing twice after a two-week washout period.

Conditions

  • Healthy Adult Females

Interventions

OTHER

Molecular hydrogen

Gas mixture containing 3.75% molecular hydrogen and ambient air.

OTHER

Placebo

Ambient air without molecular hydrogen.

Sponsors & Collaborators

  • Palacky University

    lead OTHER

Principal Investigators

  • Tereza Rysava · Palacky University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-22
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07644000 on ClinicalTrials.gov