Adaptive Daily MR-Guided Adjuvant Pelvic Therapy-Endometrial Cancer
NCT07643012 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-07-06
Summary
To evaluate the safety, tolerability, and preliminary efficacy of moderately hypofractionated (15-fraction) MR-guided adaptive pelvic IMRT in patients with endometrial cancer.
Conditions
Interventions
- RADIATION
-
MR-guided adaptive pelvic intensity-modulated radiation therapy (IMRT)
Participants receive moderately hypofractionated MR-guided adaptive pelvic intensity-modulated radiation therapy (IMRT) delivered via MR-linac to a total dose of 42 Gy in 15 fractions with daily onboard MRI guidance and online adaptive replanning as needed to optimize target coverage and minimize radiation exposure to surrounding organs at risk.
Sponsors & Collaborators
-
Rutgers, The State University of New Jersey
lead OTHER
Principal Investigators
-
Lara M Hathout · Rutgers University - Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-06-09
- Primary Completion
- 2029-06-30
- Completion
- 2029-06-30
- FDA Device
- Yes
Countries
- United States
Study Locations
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