MedTrace Logo

Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia

NCT07640607 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 82

Last updated 2026-07-07

No results posted yet for this study

Summary

Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization. While both mechanisms have been independently associated with disease severity, their interrelationship remains unclear. This cross-sectional study aims to investigate whether central sensitization symptoms mediate the relationship between conditioned pain modulation and fibromyalgia impact.

Conditions

  • Fibromyalgia (FM)
  • Quantitative Sensory Testing
  • Central Sensitization
  • PRESSURE PAIN THRESHOLD
  • Pain Perception

Interventions

OTHER

Clinical Scales

Central Sensitization Inventory, Revised Fibromyalgia Impact Questionnaire, S-LANSS, Tampa Kinesiophobia Scale, Hospital Anxiety and Depression Scale, SF-12 Quality of Life Scale and Fatigue Severity Scale

OTHER

Quantitative Sensory Tests(QST) protocol

including PPT Measurement with an Algometer, CPM and the Slow-Repeated Stimulated Pain Assessment Protocol

Sponsors & Collaborators

  • Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

    lead OTHER

Principal Investigators

  • Feyza Nur Yücel, Assoc. Prof. · Saglik Bilimleri Universitesi

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-07-01
Primary Completion
2026-08-30
Completion
2026-09-01

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07640607 on ClinicalTrials.gov