Standardising Terminology, Classification, Diagnostic Recognition and Reporting of Patient-ventilator Interactions: Protocol for an International Delphi Consensus Study

Summary

Patient-ventilator interaction describes how a mechanically ventilated patient's breathing effort aligns with ventilator support. Terminology and classification of abnormal patient-ventilator interaction remain inconsistent across clinical practice, research, and education. The INTERACT study is an international modified Delphi consensus study that will invite multidisciplinary experts to rate and refine statements on terminology, classification, diagnostic recognition, and reporting standards for patient-ventilator interaction. The study aims to develop an internationally agreed glossary, taxonomy, and minimum reporting dataset to improve communication, education, research comparability, and future automated detection systems.

Conditions

• Patient-Ventilator Interaction
• Asynchrony, Patient-Ventilator

Interventions

OTHER

Modified Delphi consensus survey

Participants will complete iterative anonymous Delphi survey rounds rating statements on patient-ventilator interaction terminology, classification, diagnostic recognition, and reporting standards. No clinical intervention will be delivered.

Sponsors & Collaborators

• Al Adan Hospital Kuwait

  lead INDUSTRY

Principal Investigators

• Ahmed S Elmasry, MD, MSc, EDIC · Department of Anaesthesia and Intensive Care Medicine, Al Adan Hospital, Ministry of Health, Kuwait.

• Denise Battaglini, MD, PhD · Anaesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy

• Marcus J Schultz, MD, PhD · Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Medical University of Vienna, Vienna, Austria

• Prashant Nasa, MD, PhD · Department of Critical Care Medicine and Anaesthesia, The Royal Wolverhampton NHS Trust, New Cross Hospital, Wolverhampton, UK; Cantonal Hospital St. Gallen, HOCH Health Ostschweiz, St. Gallen, Switzerland;

• Pedja Kovacevic, MD, PhD · University Clinical Centre of the Republic of Srpska, Medical Intensive Care Unit, Banja Luka, Republic of Srpska, Bosnia and Herzegovina; Faculty of Medicine, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina

• Juliana C Ferreira, MD, PhD · Department of Pulmonology, Divisao de Pneumologia, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil.

• Patricia R Rocco, MD, PhD · 9-10- Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

• Ehab G Daoud, MD, PhD · Department of Internal Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, USA

• Annemijn H Jonkman, MD, PhD · Department of Adult Intensive Care, Erasmus Medical Centre, Rotterdam, The Netherlands

• Ali A Hssain, MD, PhD · Medical Intensive Care Unit / ECMO Team, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar

• Mohammed A Fakher, MD, PhD · Critical Care Medicine Department, Faculty of Medicine, Cairo University, Egypt.

• Francesca Collino · Department of Surgical Science, University of Turin, Turin, Italy

Eligibility

Min Age

30 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2026-09-01

Primary Completion

2027-03-01

Completion

2027-06-01

Countries

• Kuwait

Study Locations