A Study of MET Concordance and Gene Profiling in 1L NSCLC (Genomet)
NCT07613424 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1000
Last updated 2026-05-29
Summary
Multicenter prospective assessment of MET concordance and tumor gene profiling in treatment-naïve NSCLC
Conditions
Interventions
- DIAGNOSTIC_TEST
-
NGS testing
NGS testing first for all participants and then cohort assignment for each participant can be derived based on NGS results.
- DIAGNOSTIC_TEST
-
MET IHC testing
the participants of cohort 1 need to do MET IHC testing.
- DIAGNOSTIC_TEST
-
PD-L1 and Her2 testing
the participants of cohort 1 need to do PD-L1 and Her2 testing.
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-31
- Primary Completion
- 2027-03-31
- Completion
- 2027-03-31
Countries
- China
Study Locations
More Related Trials
-
SERS-Based Serum Molecular Spectral Screening for Hematogenous Metastasis
NCT06772363 ·Status: NOT_YET_RECRUITING
-
Evaluating Mutations in MET and TP53 Among Patients Diagnosed With Squamous Cell Carcinoma
NCT03938012 ·Status: UNKNOWN
-
Genomic Profiling in Previously Untreated Metastatic Non-small Cell Lung Cancer
NCT02671045 ·Status: TERMINATED
-
To Evaluate the Correlation Between the Results of Specific Gene Testing and the Efficacy of Targeted Therapy in Patients With NSCLC
NCT05805267 ·Status: COMPLETED
-
Genomic Study in Non-small Cell Lung Cancer Brain Metastasis
NCT04745715 ·Status: COMPLETED
-
A Multi-center Prospective Observational Biomarker Study on EGFRm+ Non-small Cell Lung Cancer Patients With Leptomeningeal Metastasis
NCT02803619 ·Status: UNKNOWN
-
Next-generation Sequencing of Small Cell Lung Cancer to Identify Susceptibility Gene and to Assess Treatment
NCT03244904 ·Status: UNKNOWN
-
Comparison of Gene Mutations in Matched Samples in Advanced Nonsquamous NSCLC Using NGS
NCT02416726 ·Status: COMPLETED ·Phase: NA
-
Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
NCT00568906 ·Status: TERMINATED
-
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
NCT05530759 ·Status: RECRUITING
-
Study of the Expression of Met Receptor Fragments in Non Small Cell Lung Cancers
NCT01647867 ·Status: COMPLETED ·Phase: NA
-
NGS-based Comprehensive Genomic ctDNA Panel in NSCLC With Immunotherapy
NCT04636047 ·Status: UNKNOWN
-
Met Non Small Cell Cancer Registry (MOMENT)
NCT05376891 ·Status: RECRUITING
-
The Predictive Value of Proteome Profiling for Brain Metastasis in Limited-Stage Small-Cell Lung Cancer
NCT06483919 ·Status: ACTIVE_NOT_RECRUITING
-
Real-World Study on Gene Profile in Patients With Advanced NSCLC Who Progressed on First-Line Osimertinib Therapy(GPS).
NCT05219162 ·Status: COMPLETED ·Phase: PHASE4
-
Molecular Imaging Visualization of Tumor Heterogeneity in Non-small Cell Lung Cancer
NCT04553601 ·Status: UNKNOWN ·Phase: NA
-
Detection of Early Metastases in Patients With Stage I Non-small Cell Lung Cancer
NCT00003006 ·Status: COMPLETED
-
Biomarkers for Diagnosis of Lung Cancer
NCT02050100 ·Status: COMPLETED
-
Analysis of Driver Gene Mutation in Early Stage Non-small Cell Lung Cancer
NCT04266691 ·Status: COMPLETED
-
EGFR Mutations on ctDNA in Patients With Advanced NSCLC
NCT02623257 ·Status: COMPLETED
-
Non Small Cell Lung Cancer Evaluation According to Pre-determined Drug-targeting Tumor Markers
NCT01141686 ·Status: COMPLETED
-
Perioperative and Postoperative Circulating Tumor Cell Monitoring in Different Stage of NSCLC
NCT07186855 ·Status: COMPLETED
-
Evaluating the Predictive Capability of Transcriptomic Profiling for Identifying the Primary Site of Metastatic Tumors
NCT07319949 ·Status: NOT_YET_RECRUITING
-
A Prospective Study to Evaluate the Consistency of Next-Generation Sequencing(NGS)-Panels by Using Malignant Hydrothorax Form NSCLC
NCT03546452 ·Status: UNKNOWN
-
Comprehensive Analysis of Gene Mutation Profile in Chinese NSCLC Patients by Next-generation Sequencing
NCT03609918 ·Status: COMPLETED