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Comparison of 5% Hypertonic Saline Versus 3% Hypertonic Saline in Resolution of Post-operative Corneal Edema.

NCT07605273 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2026-05-22

No results posted yet for this study

Summary

There is a lack of data to determine the comparative advantages of 5% hypertonic saline and 3% hypertonic saline over the other. Hence, the current study was planned to determine their comparative effectiveness by comparing the change in means of central corneal thickness in the groups receiving 3% hypertonic saline and 5% hypertonic saline eyedrops developing post-phacoemulsification corneal edema.

Conditions

  • Corneal Edema

Interventions

DRUG

5% Hypertonic Saline

Patients received 5% hypertonic saline 2 hourly for the first 24 hours and then four times daily for the next 6 days.

DRUG

3% Hypertonic Saline

Patients received 3% hypertonic saline 2 hourly for the first 24 hours and then four times daily for the next 6 days.

Sponsors & Collaborators

  • Muhammad Aamir Latif

    lead OTHER

Principal Investigators

  • Anum Amin · Pakistan Air Force (PAF) hospital/Fazaia Post Graduate Medical Institute, Islamabad

  • Muhammad Azam, FCPS · Pakistan Air Force (PAF) hospital/Fazaia Post Graduate Medical Institute, Islamabad

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-01
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07605273 on ClinicalTrials.gov