MedTrace Logo

Studying Fatigue and Movement After Stroke

NCT07594938 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2026-05-19

No results posted yet for this study

Summary

The goal of this observational study is to learn how neuromuscular fatigue develops after stroke and how changes in brain activity, muscle activity, and their interaction contribute to reduced motor performance in stroke survivors compared to healthy individuals. The study will include adults with a first-ever stroke in the subacute phase and age-matched healthy volunteers.

The main questions it aims to answer are:

* How does neuromuscular fatigue develop during repeated muscle contractions after stroke compared to healthy individuals?
* How do brain activity, muscle activity, and brain-muscle interaction change during fatigue after stroke?

Researchers will compare stroke participants and healthy control participants to determine whether fatigue-related changes are more strongly associated with altered brain activity, altered muscle activity, or disrupted brain-muscle communication after stroke.

Participants will:

* Perform repeated leg muscle contractions until fatigue while seated in an experimental setup
* Wear non-invasive sensors to record brain activity (EEG) and muscle activity (EMG) during the task
* Complete the study during a single experimental session in which fatigue-related changes will be measured throughout the task

Conditions

  • Stroke
  • Cerebro-vascular Accident
  • Ischemia Stroke
  • Hemorrhage Stroke

Sponsors & Collaborators

  • Vrije Universiteit Brussel

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2029-10-31
Completion
2029-10-31

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07594938 on ClinicalTrials.gov