AI-Driven Metabolic Cohort in Overweight/Obese Chinese Adults
NCT07584330 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 2800
Last updated 2026-05-13
Summary
The goal of this observational cohort study is to delineate the five-year dynamic trajectories of metabolic phenotypes in Chinese adults with overweight or obesity, with or without type 2 diabetes, focusing on transition rates from metabolically healthy overweight/obesity to unhealthy overweight/obesity or to type 2 diabetes, as well as the incidence and progression of diabetic complications and cardiovascular events in those with type 2 diabetes and overweight/obesity. Researchers will compare three phenotype groups, namely metabolically healthy overweight/obesity, metabolically unhealthy overweight/obesity, and type 2 diabetes with overweight/obesity, to assess differences in metabolic parameter changes, complication rates, and cardiovascular risk. Participants will use a digital health management platform for data upload and lifestyle support, and will complete comprehensive health assessments at baseline, at 2.5 years, and at 5 years, along with annual light follow-ups.
Conditions
- Overweight and Obesity
- Diabetes Mellitus, Type 2
- Prediabetic State
- Metabolic Syndrome
Sponsors & Collaborators
-
Zhujiang Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2032-04-01
- Completion
- 2032-04-01
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