A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or Obesity
NCT07557953 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2026-05-15
Summary
The study is testing cagrilintide, a study medicine, to understand how it affects food intake and appetite in people with overweight or obesity. Participants will receive either cagrilintide or placebo, and which treatment participants get is decided by chance. Cagrilintide is the treatment being tested, while placebo looks like the study medicine but does not contain any active medicine. The study will last for about 30 weeks.
Conditions
Interventions
- DRUG
-
Cagrilintide is administered subcutaneously .
- DRUG
-
Placebo Cagrilintide
Placebo Cagrilintide is administered subcutaneously.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Clinical Transparency' (dept. 2834) · Novo Nordisk A/S
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-30
- Primary Completion
- 2027-04-13
- Completion
- 2027-04-13
- FDA Drug
- Yes
Countries
- Germany
Study Locations
More Related Trials
-
A Study on How NNC0174-1213 Works in People With Overweight or Obesity.
NCT06719011 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
NCT07184086 ·Status: RECRUITING ·Phase: PHASE1
-
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight
NCT05996848 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study Looking at How NNC0487-0111 Affects Food Intake, Appetite and Metabolism After Meals in People With Obesity
NCT07508020 ·Status: RECRUITING ·Phase: PHASE1
-
A Trial to Assess the Effect of Liraglutide on Gastric Emptying in Healthy Obese Volunteers
NCT00978393 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
NCT06780449 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body
NCT05564104 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight
NCT07357766 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight
NCT06388187 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study to Look at How Semaglutide Affects Gastric Emptying in People With Obesity
NCT03842202 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Liraglutide Compared to Glimepiride on Appetite in Subjects With Type 2 Diabetes
NCT01511692 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity
NCT05236517 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
NCT05394519 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity
NCT04940078 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term
NCT07011667 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight
NCT04779697 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
NCT06577766 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Methodology Study To Examine 6-Week Food Intake With Liraglutide In Obese Subjects
NCT03041792 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Liraglutide on Weight and Appetite in Obese Subjects With Type 2 Diabetes
NCT01508949 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of TG103 Injection in Overweight or Obesity
NCT05299697 ·Status: UNKNOWN ·Phase: PHASE2
-
Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)
NCT07527195 ·Status: RECRUITING ·Phase: PHASE1
-
The Role of the Amylin Analogue Cagrilintide in Bone Metabolism
NCT07010432 ·Status: RECRUITING ·Phase: PHASE1
-
A Research Study Looking at How Cagrilintide Works on the Heart Rhythm in Healthy Participants
NCT05804162 ·Status: COMPLETED ·Phase: PHASE1
-
Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548987 ·Status: COMPLETED ·Phase: PHASE3