The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients

NCT07541222 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2026-05-06

No results posted yet for this study

Summary

This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.

Conditions

  • Hypotension on Induction
  • Cardiac Surgery
  • Antihypertensive Agents
  • Anesthesia, Intravenous
  • Hemodynamics

Interventions

OTHER

Chronic Antihypertensive Medication Use

Patients' chronic antihypertensive drug use (number of drugs and pharmacological classes) will be recorded. This is an observational study where existing medication regimens (ACE inhibitors, ARBs, Beta-blockers, Calcium Channel Blockers, Diuretics) are documented to analyze their impact on the post-induction hypotension burden (MAP \< 55 mmHg).

Sponsors & Collaborators

  • Konya City Hospital

    lead OTHER

Principal Investigators

  • Mustafa Aydemir, MD · Konya City Hospital

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2026-11-01
Completion
2026-12-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07541222 on ClinicalTrials.gov