The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
NCT07541222 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 160
Last updated 2026-05-06
Summary
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.
Conditions
- Hypotension on Induction
- Cardiac Surgery
- Antihypertensive Agents
- Anesthesia, Intravenous
- Hemodynamics
Interventions
- OTHER
-
Chronic Antihypertensive Medication Use
Patients' chronic antihypertensive drug use (number of drugs and pharmacological classes) will be recorded. This is an observational study where existing medication regimens (ACE inhibitors, ARBs, Beta-blockers, Calcium Channel Blockers, Diuretics) are documented to analyze their impact on the post-induction hypotension burden (MAP \< 55 mmHg).
Sponsors & Collaborators
-
Konya City Hospital
lead OTHER
Principal Investigators
-
Mustafa Aydemir, MD · Konya City Hospital
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2026-11-01
- Completion
- 2026-12-01
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
The Effects of Anesthesia on Cerebral Perfusion in Patients With High Blood Pressure
NCT04587401 ·Status: COMPLETED ·Phase: NA
-
Norepinephrine Weaning Guided by the Hypotension Prediction Index in Vasoplegic Shock After Cardiac Surgery
NCT05922982 ·Status: RECRUITING ·Phase: NA
-
Correlation Between Postoperative Blood Pressure Variability, Perfusion Index and Perioperative Adverse Events in Cardiac Surgery
NCT07316634 ·Status: NOT_YET_RECRUITING
-
Individualized Versus Conventional Perioperative Blood Pressure Management
NCT06225453 ·Status: RECRUITING ·Phase: NA
-
Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery
NCT06814054 ·Status: RECRUITING
-
Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
NCT07497295 ·Status: RECRUITING
-
Hypotension Prediction During Cardiac Surgery Postoperative Period
NCT05840432 ·Status: UNKNOWN
-
Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery
NCT05637164 ·Status: UNKNOWN ·Phase: NA
-
Norepinephrine Prevent Post-induction Hypotension in High-risk Patients
NCT06028256 ·Status: UNKNOWN ·Phase: PHASE4
-
Decision Support for Intraoperative Low Blood Pressure
NCT02726620 ·Status: COMPLETED ·Phase: NA
-
Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment
NCT07396636 ·Status: RECRUITING
-
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
NCT07294040 ·Status: RECRUITING
-
Personalized Blood Pressure Management
NCT03442907 ·Status: COMPLETED ·Phase: NA
-
Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery
NCT04151264 ·Status: COMPLETED ·Phase: NA
-
Echocardiography-derived Pre-induction Hemodynamic Phenotypes and Post-induction Hypotension: an Exploratory Clustering Analysis
NCT07509255 ·Status: COMPLETED
-
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
NCT05430724 ·Status: COMPLETED ·Phase: NA
-
Carotid Doppler Parameters and Post-Induction Hypotension
NCT07385274 ·Status: COMPLETED
-
Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery
NCT07324694 ·Status: RECRUITING
-
NORepinephrine-Maintaining-individuaALIZEd Blood Pressure
NCT03715712 ·Status: COMPLETED ·Phase: NA
-
Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension
NCT05171608 ·Status: COMPLETED ·Phase: NA
-
Carotis cFT In Prediction Of Hypotension
NCT05896514 ·Status: COMPLETED
-
Individualized Blood Pressure Management in Patients Undergoing Cardiac Surgery
NCT03784690 ·Status: WITHDRAWN ·Phase: NA
-
Prevention or Treatment of Arterial Hypotension and Oxygen Cerebral Saturation During Major Abdominal Surgery
NCT05481047 ·Status: COMPLETED ·Phase: NA
-
Permissive Hypotension After Cardiac Surgery
NCT06476613 ·Status: COMPLETED ·Phase: NA
-
Continuous Vs Intermittent Non Invasive Blood Pressure Monitoring in Preventing Post Operative Organ Failure
NCT05496322 ·Status: COMPLETED ·Phase: NA