Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
NCT07294040 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 140
Last updated 2025-12-19
Summary
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia. PIH is defined as a drop in mean arterial pressure of ≥30% from baseline or below 65 mmHg within the first 20 minutes after anesthesia induction, prior to surgical stimulation.
The primary objective is to determine the frequency of PIH in elderly oncology patients. Secondary objectives include evaluating the association of PIH with age, ASA score, cancer type, oncological treatments (chemotherapy/radiotherapy), comorbidities, medication use, anemia, biochemical parameters, and preoperative perfusion index (PI) and pleth variability index (PVI).
Findings from this study are expected to contribute to improved perioperative management and to the development of tailored anesthesia protocols for geriatric oncology patients.
Conditions
- Post-induction Hypotension (PIH)
- Geriatric Patient
- Oncologic Disease
- Hemodynamic Effects of General Anesthesia
- Risk Factors Associated With Anesthesia-Induced Hypotension
Sponsors & Collaborators
-
Dolunay ARIK
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-25
- Primary Completion
- 2026-05-25
- Completion
- 2026-05-25
Countries
- Turkey (Türkiye)
Study Locations
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