Development of an Active Heat Dissipation Device Based on Thermoelectric Cooling Technology: Aiming to Improve Endurance Sports Performance

NCT07539714 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-04-20

No results posted yet for this study

Summary

This project investigates the effectiveness of pre-exercise active cooling using a temperature-controlled cooling vest in reducing heat-related physiological strain during endurance-type aerobic exercise in non-regularly trained ("weekend") athletes under hot and humid environmental conditions. Because these individuals often lack sufficient heat-acclimation training, they are at increased risk of excessive thermal stress, cardiovascular overload, and heat-related disorders during prolonged exercise.

Using a controlled laboratory design, participants will perform moderate-intensity endurance exercise in a simulated hot environment, with or without pre-cooling intervention. Peripheral circulation and thermoregulatory responses will be assessed through laser Doppler flowmetry based skin blood-flow analysis and infrared thermography, alongside heart rate and perceived exertion measures.

The study aims to clarify how active pre-cooling influences vascular regulation, sympathetic activity, skin temperature distribution, and exercise tolerance, and to evaluate its potential as a practical, non-fatiguing alternative to heat-acclimation training. The findings are expected to provide evidence-based guidance for reducing heat strain and improving exercise safety and comfort in recreational endurance athletes exercising in hot climates.

Conditions

  • Heat Stroke

Interventions

DEVICE

TEC Vest

Intervention 1: Active Pre-Cooling Vest Type: Device (active cooling garment) Timing: 30 minutes before exercise (pre-cooling period) Procedure: Participants wear the temperature-controlled vest in a hot/humid lab setting before the endurance aerobic exercise test. Purpose: Reduce thermal strain and cardiovascular load; improve comfort; modulate peripheral circulation responses.

OTHER

No Pre-Cooling (Without Vest)

Intervention 2: No Pre-Cooling Without Vest Type: No intervention / usual condition Timing: 30 min Duration Procedure: Participants rest quietly for the same pre-exercise duration without wearing a cooling vest, then complete the identical warm-up and exercise protocol.

DEVICE

Water Cooled Vest

Type: Device (active cooling garment) Timing: 30 minutes before exercise (pre-cooling period) Procedure: Participants wear the water cooled vest in a hot/humid lab setting before the endurance aerobic exercise test. Purpose: Reduce thermal strain and cardiovascular load; improve comfort; modulate peripheral circulation responses.

Sponsors & Collaborators

  • Kaohsiung Medical University

    lead OTHER

Principal Investigators

  • Guo LY Professor and Dean of College of Health Sciences, P.hD · Department of Sports Medicine, Kaohsiung Medical University, Taiwan

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-02-01
Primary Completion
2027-02-28
Completion
2027-05-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07539714 on ClinicalTrials.gov