Impacts of Oral Irrigation in Patients With Periimplant Mucositis

Summary

The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine TGF-β1, IL-1β, t-PA, and PAI-1 levels in periimplant crevicular fluid of patients with periimplant mucositis. The null hypothesis was that oral irrigators would be effective compared to interdental brush in the oral care of individuals who use implant-supported protheses.

Conditions

• Peri-implant Mucositis

Interventions

DIAGNOSTIC_TEST

Periimplant crevicular fluid (PICF) collection

Prior to PICF sampling, supragingival plaque was removed by sterile curets and, after air drying, the surfaces were isolated by cotton rolls. Filter paper strips (periopaper, proflow Inc., Amityville, New York, USA) were placed in sulcus for 30s. Care was taken not to avoid mechanical trauma and strips contaminated with blood or saliva were discarded. The absorbed PICF volume was estimated by a calibrated instrument (periotron 8000, proflow Inc., Amityville, NY, USA). Then, the strips were sealed into sterile tubes before freezing at -80⁰C. The readings were converted to an actual volume (µl) by reference to the standard curve.

Sponsors & Collaborators

• Ondokuz Mayıs University

  lead OTHER

Principal Investigators

• Burcu OZKAN CETINKAYA, Prof · Ondokuzmayis University, Faculty of Dentistry, Department of Periodontology,

• Sema TUTUNCUOGLU, Dr · Samsun Oral and Dental Health Hospital, Samsun, Turkey

• Ferda PAMUK, Assoc. Prof. · Beykent University, Faculty of Dentistry, Department of Periodontology

• Bahattin AVCI, Assoc. Prof. · Ondokuzmayis University, Faculty of Medicine Department of Biochemistry

• Gonca Cayir KELES, Prof · Okan University, Faculty of Dentistry, Department of Periodontology

• Muge LUTFIOGLU, Assoc. Prof. · Ondokuzmayis University, Faculty of Dentistry, Department of Periodontology

• Şevki GULER, Assist.Prof. · Izzet Baysal University, Faculty of Dentistry, Department of Periodontology

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

45 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-11-06

Primary Completion

2015-05-04

Completion

2015-06-05