MedTrace Logo

Lily's Grace Temporal Interference

NCT07520955 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-05-01

No results posted yet for this study

Summary

This study is to evaluate the effectiveness of targeted Transcranial Electrical Stimulation with Temporal Interference (TES-TI) interventions to boost Non-Rapid Eye Movement (NREM) sleep, decrease seizures and promote emotional health in patients with epilepsy. Up to 24 participants (8 control participants for technical optimization prior to recruitment and 16 patients with epilepsy) will be enrolled and can expect to be on study for up to 24 months.

Conditions

Interventions

DEVICE

TES-TI

Real stimulation will take place on visits 2 - 5 or visits 6 - 10.

OTHER

Sham Stimulation

Sham stimulation will take place on visits 2 - 5 or visits 6 - 10.

OTHER

Structural and Functional MRI

After baseline night visit 1 and before intervention visits 2 - 10. MRI is used to help determine electrode placement.

Sponsors & Collaborators

  • Lily's Fund for Epilepsy Research

    collaborator UNKNOWN

  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • Melanie Boly, MD, PhD · UW School of Medicine and Public Health

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-31
Primary Completion
2028-04-30
Completion
2028-04-30
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07520955 on ClinicalTrials.gov