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Clinical and Radiographic Evaluation of CGF and Alloplastic Grafting in Participants Undergoing the Socket Shield Technique for Immediate Anterior Maxillary Implant Placement. This Study Assesses Bone Healing and Stability When Managing the Crestal Gap in the Esthetic Zone.

NCT07514871 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2026-04-07

No results posted yet for this study

Summary

The goal of this clinical trial is to evaluate the clinical and radiographic effectiveness of the socket shield technique combined with concentrated growth factor (CGF) and alloplastic graft in promoting bone healing and achieving successful immediate implant placement in the esthetic zone.

This prospective case series involves both male and female participants aged 18 years or older who require immediate implant placement in the maxillary anterior segments. The main questions it aims to answer are :

Does the combined use of CGF and alloplastic grafting materials with the socket shield technique improve crestal bone levels as measured by CBCT?

How does this intervention affect secondary outcomes such as primary implant stability measured via the Osstell implant stability quotient?

Participants will: Undergo a socket shield procedure (partial extraction therapy) where the labial root fragment is retained to preserve the buccal bone. Provide a blood sample for the preparation of autologous CGF. Receive simultaneous immediate implant placement. Have a "sticky bone" mixture of CGF and alloplastic graft packed into the jumping gap around the implant. Attend follow-up appointments for clinical assessments and CBCT imaging at 2 weeks and 6 months post-operatively.

Conditions

  • Alveolar Ridge Resorption
  • Bone Loss in the Esthetic Zone
  • Socket Shield Technique
  • Partial Extraction Therapy
  • Immediate Dental Implant Placement
  • Bone Regeneration Using Concentrated Growth Factor
  • Alloplastic Bone Grafting

Interventions

PROCEDURE

Socket Shield Technique with CGF and Alloplastic Graft.

The intervention consists of a specialized surgical and regenerative protocol that combines the Socket Shield Technique with the application of a "sticky bone" complex for simultaneous immediate implant placement. Unlike conventional extraction, this partial extraction therapy involves decapitating the tooth crown and sectioning the root mesiodistally to retain a labial segment, which is remains firmly attached to the buccal bone to provide structural support. Following the immediate insertion of the dental implant, a third-generation platelet concentrate known as Concentrated Growth Factor (CGF) is prepared from the patient's blood using a variable spin-speed centrifuge to create a dense fibrin network rich in growth factors. This autologous CGF is then combined with a synthetic alloplastic bone graft to form the "sticky bone" mixture, which is carefully packed into the "jumping gap" between the implant periphery and the retained labial shield to facilitate enhanced bone regeneration

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Tarek El-Ghareeb, professor · Cairo University

  • Abdelmoez Mohamed El-Sharkawy, Associate Professor · Cairo University

  • Ibrahim Ahmad Anas Jadoo · Cairo University

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-25
Primary Completion
2026-10-01
Completion
2026-11-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07514871 on ClinicalTrials.gov