A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults
NCT07513571 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2026-05-11
Summary
The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laroprovstat in healthy male and female participants.
Conditions
- Healthy Participants
Interventions
- DRUG
-
AZD4954
AZD4954 will be administered orally.
- DRUG
-
Laroprovstat
Laroprovstat will be administered orally.
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-04-10
- Primary Completion
- 2026-07-09
- Completion
- 2026-07-09
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
NCT00902993 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluate Different Extended-release (ER) Tablets/Capsules of AZD1305
NCT00689403 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers
NCT01037725 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
NCT01121302 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers
NCT01051505 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Multiple Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
NCT01171105 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years
NCT07455825 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Healthy Volunteers, Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] AZD8931
NCT01284595 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD1446 Administered for 4 Weeks in Elderly Healthy Volunteers
NCT00997308 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Determine the Effect of Food on the Pharmacokinetics of Oral AZD8931 Tablets
NCT00879346 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, and Pharmacokinetics of AZD7268 After Single Ascending Oral Doses in Healthy Subjects
NCT00796965 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
NCT01330758 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
NCT00803855 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses ofAZD2551
NCT00860353 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers
NCT06951880 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.
NCT05457270 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 in Healthy Volunteers
NCT00940212 ·Status: COMPLETED ·Phase: PHASE1
-
Study of an Extended Release (ER) Tablet, Single and Repeated Dosing
NCT00689039 ·Status: COMPLETED ·Phase: PHASE1
-
To Study the Absorption, Distribution, Metabolism and Excretion of AZD1305
NCT00689247 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I, Safety Tolerability and Pharmacokinetics of AZD4831 to Treat Cardiovascular Disease
NCT03136991 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of the Safety and Pharmacokinetics of Single and Multiple Oral Doses of AZD4316 in Healthy Subjects
NCT01247103 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults
NCT06469151 ·Status: COMPLETED ·Phase: PHASE1
-
To Evaluate the Effect of Food on the Pharmacokinetics (PK) of AZD0328
NCT00752830 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
NCT06980428 ·Status: RECRUITING ·Phase: PHASE1
-
Investigating Safety, Tolerability and Pharmakinetics When Giving Single and Fractionated Doses of AZD3241 to Healthy Volunteers
NCT00729443 ·Status: COMPLETED ·Phase: PHASE1