To Study the Absorption, Distribution, Metabolism and Excretion of AZD1305
NCT00689247 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2010-12-03
Summary
The purpose of this study is to learn more about how AZD1305 is handled by the body, i.e the absorption, distribution, metabolism and excretion of AZD1305.
Conditions
- Healthy
Interventions
- DRUG
-
AZD1305
oral solution, single dose
- DRUG
-
AZD1305
iv infusion, single dose
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Helen Lunde, MD · AstraZeneca R&D, Mölndal, Sweden
-
Raj Chetty, MBBS, MD · AstraZeneca CPU Alderley Park, United Kingdom
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 35 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-04-30
- Primary Completion
- 2008-05-31
- Completion
- 2008-05-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
AZD1722 Open Label, Absorption Distribution Metabolism and Excretion Study
NCT02063386 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study to Assess Absorption, Metabolism & Excretion of a Single Oral Dose [14C]AZD0530 in Healthy Male Volunteers
NCT00853983 ·Status: COMPLETED ·Phase: PHASE1
-
Study of an Extended Release (ER) Tablet, Single and Repeated Dosing
NCT00689039 ·Status: COMPLETED ·Phase: PHASE1
-
Single Oral Dose of 60 mg [14C]AZD9668 in Healthy Male Volunteers
NCT01147549 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Drug Concentrations in Plasma of Different Extended-release Formulations of AZD1305
NCT00957437 ·Status: COMPLETED ·Phase: PHASE1
-
To Study Safety, Tolerability and Pharmacokinetics of AZD1305 in Healthy Male Japanese Subjects
NCT00738322 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043
NCT01086813 ·Status: WITHDRAWN ·Phase: PHASE1
-
Phase I, Exploratory, Single Centre, Single Oral Dose AZD9668 and Intravenous Microdose of [C14] AZD9668, Healthy Subject
NCT01161355 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of the Safety and Pharmacokinetics of Single and Multiple Oral Doses of AZD4316 in Healthy Subjects
NCT01247103 ·Status: WITHDRAWN ·Phase: PHASE1
-
To Assess the Safety, Tolerability and Pharmacokinetics of AZD2820 After Single Ascending Doses
NCT01332214 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Activity of AZD5122 When Given as a Single Dose to Healthy Male Subjects
NCT00984477 ·Status: COMPLETED ·Phase: PHASE1
-
Investigation of Rate+Extent of Excretion of Radioactivity in Urine+Faeces After Oral Administration of [14C]AZD1386
NCT00832169 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers
NCT01051505 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Activity of AZD5069 When Given as a Single Dose to Healthy Male and/or Female Subjects
NCT00953888 ·Status: COMPLETED ·Phase: PHASE1
-
Exploratory Study to Assess the Pharmacokinetics of AZD5985
NCT00799331 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566.
NCT00844103 ·Status: COMPLETED ·Phase: PHASE1
-
To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Administration of AZD8329
NCT01207089 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of AZD8566.
NCT00749333 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety and Tolerability Single Ascending Doses of AZD4017
NCT00791752 ·Status: COMPLETED ·Phase: PHASE1
-
A Study in Healthy Volunteers to Assess the Tolerability and Blood Levels of a Single Dose of AZD7687
NCT01046357 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses ofAZD2551
NCT00860353 ·Status: TERMINATED ·Phase: PHASE1
-
AZD0914 Phase 1 ADME Study in Healthy Volunteers
NCT02298920 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
NCT00803855 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety, Tolerability and Pharmacokinetics After Single Ascending Intravenous Doses of AZD2927 in Healthy Male Volunteers
NCT01264250 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
NCT00902993 ·Status: COMPLETED ·Phase: PHASE1