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Observational Cohort Study of Chronic Viral Infection in the Central Nervous System

NCT07512518 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 66

Last updated 2026-04-06

No results posted yet for this study

Summary

This research team intends to conduct a real-world cohort study of chronic CNS viral infections represented by PML, to evaluate whether administration of immune checkpoint inhibitors improves long-term outcomes in this patient population.Patients with prior follow-up will be enrolled into a retrospective/prospective ambidirectional cohort, and newly diagnosed patients will be enrolled into a prospective cohort.

Conditions

  • Progressive Multifocal Leukoencephalopathy
  • Immune Checkpoint Inhibitors

Interventions

DRUG

Immune Checkpoint Inhibitors

Immune Checkpoint Inhibitors for PML treatment

Sponsors & Collaborators

  • Peking Union Medical College Hospital

    lead OTHER

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-20
Primary Completion
2030-10-25
Completion
2030-10-25

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07512518 on ClinicalTrials.gov