Combination Effect of Proprioceptive Training and Transcranial Magnetic Stimulation on Selected Gait Kinematic Parameters in Stroke Patients

Summary

this study was done to investigate the Combination effect of proprioceptive training and transcranial magnetic stimulation on selected gait kinematic parameters in stroke patients.

Conditions

• Transcranial Magnetic Stimulation
• Stroke
• Gait Disorders, Neurologic
• Proprioceptive Training

Interventions

DEVICE

Transcranial Magnetic Stimulation

Transcranial Magnetic Stimulation (TMS) is a non-invasive method that uses magnetic fields to stimulate brain nerve cells through figure-eight or circular coils with strengths of 1.5 to 3.0 Tesla. The TMS pulses, lasting about 100 microseconds, can be adjusted to induce excitatory or inhibitory responses, with a focus on specific brain regions. Although Transcranial Magnetic Stimulation is safe with mild side effects, its efficacy declines with depth. It is commonly used in treating depression and anxiety, as well as in cognitive neuroscience research, often employing a protocol of high-frequency Transcranial Magnetic Stimulation (≥5 Hertz) for 20 minutes on the lower limb region of the bilateral cerebrum at 90% of the motor threshold.

OTHER

selected physical therapy program

The program provides a set of exercises focused on improving ankle and knee movements, building muscle strength, and increasing the range of motion. It details eight activities: Ankle Movements for controlling foot actions; Active Knee Extension to strengthen the quadriceps; Gluteus maximus Squeezes for gluteal muscle enhancement; Inner Range Quadriceps involving a towel for knee support; Bridging to elevate the pelvis; a Passive Stretching Program for gentle knee stretches; Trunk Rotation to improve mobility; and Ankle Flexion to bend the ankle without foot rotation. The exercises are designed for gradual progression based on patient tolerance.

OTHER

proprioceptive training

The program outlines techniques for enhancing patient mobility and balance through various exercises. In modified plantigrade, patients practice stepping forward and backward while weight shifting, facilitated by a therapist's manual contact on the pelvis. Activities with footprint markers encourage active stepping, while resisted stepping involves pushing against elastic resistance. Utilizing a wobble board helps patients maintain balance and perform self-initiated tilts to improve stability. Prerequisite exercises for stair climbing, such as bridging and sit-to-stand transfers, include verbal cues to guide weight shifts and step placements, progressing from low to standard steps with therapist assistance as necessary.

Sponsors & Collaborators

• Cairo University

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

50 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-12-01

Primary Completion

2025-08-01

Completion

2025-10-01

Countries

• Egypt

Study Locations