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Pacing In Organ Donors (the POD Trial)

NCT07505589 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3

Last updated 2026-04-08

No results posted yet for this study

Summary

The goal of this clinical trial is to test the feasibility of pacing the phrenic nerve to stimulate the diaphragm in order to improve the lung function in brain dead organ donors. The main questions it aims to answer are:

* Proof of concept and feasibility
* Can lung function be improved in lungs that have been disqualified for donation

Participants will have an AeroPace catheter inserted and will be paced on every breath up to the time of organ donation.

Conditions

  • Lung
  • Organ Donation
  • Mechanical Ventilation

Interventions

DEVICE

Lungpacer AeroPace catheter and device

Diaphragm neurostimulation device for phrenic nerve pacing during mechanical ventilation.

Sponsors & Collaborators

  • Lotte & John Hecht Memorial Foundation

    collaborator OTHER

  • Lungpacer Medical Inc.

    collaborator INDUSTRY

  • Fraser Health

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
19 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-31
Primary Completion
2025-12-01
Completion
2025-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07505589 on ClinicalTrials.gov