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Effect of Early Time-Restricted Eating on Appetite, Appetite-Regulatory Hormones and Energy Intake

NCT07500792 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2026-04-16

No results posted yet for this study

Summary

This randomised crossover study's primary aim is to investigate the effect of short-term fasting (eTRE) on subjective appetite and appetite-regulatory hormones (i.e., leptin, adiponectin, total glucagon-like peptide-1 (GLP-1), gastric inhibitory polypeptide (GIP), total peptide YY (PYY), acylated ghrelin and Insulin). In addition, to examine if the one-day early time-restricted eating influences energy expenditure and ad libitum energy intake in the periods following the standard meal test. The researchers will compare normal eating with early Time-Restricted Eating (eTRE) in healthy men.

Conditions

  • Healthy Adult Male

Interventions

DIETARY_SUPPLEMENT

Normal diet

The participants will consume three meals in 12 hours, each providing 33% of their estimated energy needs.

DIETARY_SUPPLEMENT

early Time-Restricted Eating (eTRE)

The participants will consume three meals in 6 hours, each providing 33% of their estimated energy needs.

OTHER

instantaneous visual analogue scale (iVAS)

Appetite ratings (hunger, satisfaction, fullness, prospective food consumption and desire to eat) will be measured by visual analogue scales (VAS).

Sponsors & Collaborators

  • University of Jazan

    collaborator OTHER_GOV

  • University of Glasgow

    lead OTHER

Principal Investigators

  • James Dorling · University of Glasgow

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2027-06-30
Completion
2027-11-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07500792 on ClinicalTrials.gov