MedTrace Logo

EUSOL vs. PDGF Dressing for Diabetic Foot Ulcers

NCT07493343 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-03-25

No results posted yet for this study

Summary

Diabetic foot ulcers are a major cause of morbidity and amputation. This randomized controlled trial will compare the efficacy of a traditional antiseptic dressing (EUSOL) with a modern biologic dressing containing Platelet-Derived Growth Factor (PDGF) in promoting wound contraction. The study aims to determine if PDGF dressing leads to better healing outcomes in patients with Grade II Wagner diabetic foot ulcers.

Conditions

  • Diabetic Wound

Interventions

PROCEDURE

EUSOL Dressing

Daily dressing with freshly prepared Edinburgh University Solution of Lime (EUSOL) applied to the ulcer after standard debridement and cleansing.

PROCEDURE

Platelet-Derived Growth Factor (PDGF) Dressing

PDGF-based topical preparation applied to the ulcer surface every fourth day, covered by a secondary dressing. Interim dressing changes used normal saline only.

Sponsors & Collaborators

  • Services Institute of Medical Sciences, Pakistan

    collaborator OTHER_GOV

  • Services Hospital, Lahore

    lead OTHER_GOV

Principal Investigators

  • Awais Amjad Malik, MBBS, FCPS · Services Institute of Medical Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2025-12-31
Completion
2026-01-10

Countries

  • Pakistan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07493343 on ClinicalTrials.gov