Apligraf Versus Standard Therapy in the Treatment of Diabetic Foot Ulcers
NCT00512538 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 82
Last updated 2007-08-07
Summary
The purpose of this study is to determine the ability of Apligraf to improve the time to and incidence of complete wound closure of diabetic foot ulcers, as compared to diabetic foot ulcers treated with standard therapy.
Conditions
- Diabetic Foot
Interventions
- DEVICE
-
Bi-layered cell therapy (Apligraf)
Sponsors & Collaborators
-
Organogenesis
lead INDUSTRY
Principal Investigators
-
Michael E Edmonds, MD · Diabetic Foot Clinic, Kings College Hospital, London UK
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-10-31
- Completion
- 2002-09-30
More Related Trials
-
Safety and Efficacy Study of APIC-PRP in Non-healing Diabetic Foot Ulcers
NCT02209662 ·Status: UNKNOWN ·Phase: NA
-
A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
NCT07159282 ·Status: RECRUITING ·Phase: PHASE4
-
Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care
NCT06564831 ·Status: RECRUITING ·Phase: NA
-
Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
NCT06437028 ·Status: RECRUITING ·Phase: NA
-
Allogenic Dermis Versus Standard Care in the Management of Diabetic Foot Ulcers
NCT02331147 ·Status: COMPLETED ·Phase: NA
-
Comparison of Human Allograft to Apligraf for Venous Leg Ulcers
NCT02047084 ·Status: ENROLLING_BY_INVITATION
-
Multiple Applications of ExpressGraft-C9T1 Skin Tissue as a Treatment for Diabetic Foot Ulcers
NCT04134143 ·Status: TERMINATED ·Phase: PHASE1
-
Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers
NCT07290673 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds
NCT05494450 ·Status: TERMINATED ·Phase: NA
-
Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers
NCT04040426 ·Status: COMPLETED ·Phase: NA
-
Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.
NCT06826339 ·Status: RECRUITING ·Phase: PHASE4
-
Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers
NCT01816633 ·Status: TERMINATED ·Phase: NA
-
Efficacy of Plasma Rich in Growth Factors (PRGF) in the Treatment of Foot Ulcers in Diabetic Patients With Peripheral Arterial Disease
NCT06952998 ·Status: RECRUITING ·Phase: PHASE4
-
Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers
NCT02036528 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
NCT07086443 ·Status: RECRUITING ·Phase: PHASE4
-
A Study Of Pain And Quality Of Life Outcomes In Subjects With a Single Painful Venous Leg Ulcer Treated With Apligraf®
NCT02011724 ·Status: UNKNOWN ·Phase: PHASE4
-
Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
NCT04065594 ·Status: COMPLETED ·Phase: NA
-
Bioengineered Skin and Wound Healing
NCT00007280 ·Status: COMPLETED ·Phase: PHASE1
-
Bioactive Smart Dressings for Diabetic Foot Ulcers: Randomized Controlled Trial
NCT05671250 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers
NCT00273234 ·Status: WITHDRAWN ·Phase: PHASE3
-
Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
NCT01353495 ·Status: COMPLETED ·Phase: NA
-
Clinical and Cost Effectiveness of Different Dressing Materials in Diabetic Foot Ulcers
NCT01105884 ·Status: WITHDRAWN ·Phase: NA
-
EPC Silver Wound Gel (EPC-123) Feasibility Study in the Management of Mildly Infected Diabetic Foot Ulcers
NCT05243810 ·Status: COMPLETED ·Phase: NA
-
A Randomized Trial on Platelet Rich Plasma Versus Saline Dressing of Diabetic Foot Ulcers
NCT04090008 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers
NCT00368693 ·Status: TERMINATED ·Phase: PHASE3