A Study of ENX-104 in Healthy Participants
NCT07472361 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2026-04-22
Summary
The study is designed to evaluate the relative bioavailability, safety, and tolerability of a single dose of ENX-104 administered orally as a solution fasted, a tablet fasted, or a tablet with a high fat meal in healthy participants
Conditions
- Healthy Volunteers
Interventions
- DRUG
-
ENX-104
Tablets
- DRUG
-
ENX-104
Oral solution
Sponsors & Collaborators
-
Engrail Therapeutics INC
lead INDUSTRY
Principal Investigators
-
David George Steel, MBChB · Parexel
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-02-25
- Primary Completion
- 2026-03-19
- Completion
- 2026-03-19
Countries
- United Kingdom
Study Locations
More Related Trials
-
A Study to Assess the Pharmacokinetics of GEn-1124 After Single Oral Dosing in Healthy Subjects
NCT07185113 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Examine the Safety, Tolerability and Biological Effects of REGN4461 in Healthy Volunteers
NCT03530514 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety and Tolerability of CDX-6114 in Healthy Volunteers
NCT03797664 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Single Ascending Doses of PF-07081532 in Healthy Adult Participants
NCT04148209 ·Status: COMPLETED ·Phase: PHASE1
-
ONO-7746 Study in Healthy Adult Subjects
NCT00956371 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.
NCT04069689 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants
NCT06281158 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04629991 in Healthy Volunteers
NCT00797342 ·Status: COMPLETED ·Phase: PHASE1
-
ONO-7746 Study in Healthy Adult Subject
NCT01106664 ·Status: COMPLETED ·Phase: PHASE1
-
Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.
NCT05628116 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PLX5622 in Healthy Adult Volunteers
NCT01282684 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers
NCT01002963 ·Status: COMPLETED ·Phase: PHASE1
-
A Study In Healthy People To Evaluate Safety, Toleration, Pharmacokinetics And Pharmacodynamics Of Multiple Oral Doses Of PF-06743649
NCT02151617 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Drug Exposure of Single Ascending Doses of BMS-986369 and the Effect of Food on the BMS-986369 in Healthy Participants
NCT05350800 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PF-06842874 in Healthy Participants
NCT04124653 ·Status: COMPLETED ·Phase: PHASE1
-
Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult Subjects
NCT01364441 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Bioavailability and Safety of DNL343 in Healthy Volunteers
NCT04581772 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0941 Following Single Oral Dose Administration in Healthy Male Subjects
NCT01474668 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study of Enlicitide and the Effect of Food in Healthy Adult Participants (MK-0616-033)
NCT06609512 ·Status: COMPLETED ·Phase: PHASE1
-
Multiple Ascending Oral Dose Phase I Study With Px-102
NCT01998672 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of PRTX-100 in Healthy Adult Volunteers
NCT00517855 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability of CFTX-1554 in Healthy Subjects
NCT05260658 ·Status: COMPLETED ·Phase: PHASE1
-
A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects
NCT02316756 ·Status: COMPLETED ·Phase: PHASE1
-
STUDY OF PF-07321332 IN HEALTHY PARTICIPANTS
NCT04756531 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1 Study of RO6806127 in Healthy Male Volunteers
NCT02196636 ·Status: COMPLETED ·Phase: PHASE1