A Study to Learn About How the Body Processes the Study Medicine Called PF-07328948 in Healthy Chinese Adults
NCT07455240 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2026-04-23
Summary
The purpose of this study is to learn about:
* How PF-07328948 is changed and removed from the body after taking
* Safety of PF-07328948
* The extent to which undesirable effects can be tolerated after taking PF-07328948 for the possible treatment of heart failure
This study is seeking participants who:
* Are healthy Chinese adults who are aged 18 years old and older
* Have body mass index from 18.5 to under 28 kilograms/meter square
* Have a total body weight over 50 kilograms (110 pounds)
* Do not have a history of blood clots blocking an artery or vein
All participants in this study will receive oral daily PF-07328948 at the study clinic for 7 consecutive days.
The experiences of the participants receiving the study medicine will be looked at. This will help to see if the study medicine is safe.
Participants will take part in this study for around 10 weeks. During this time, participants will have 1 study visit at the study clinical and 1 contact over the phone.
Conditions
- Healthy Participant
Interventions
- DRUG
-
PF-07328948
Oral tablet
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-03-02
- Primary Completion
- 2026-04-15
- Completion
- 2026-04-15
Countries
- China
Study Locations
More Related Trials
-
A Study to Understand the Effect of Low-Fat and High-Fat Meals on the Medicine Called PF-07284890 in Healthy Adults
NCT05349864 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How Different Amounts of the Study Medicine Called PF-07328948 Are Tolerated and Act in the Body in Healthy Adults
NCT05807490 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine PF-07321332 and Ritonavir in Adult Healthy Chinese Participants.
NCT05339334 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-human Study of Single Doses of PF-07328948 Which is Given to Healthy Adult Participants
NCT05654181 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine PF-07853578 and How it Acts in the Bodies of Healthy Adults
NCT05890105 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine Called PF-07054894 in People of Japanese Origin
NCT06327880 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Assess The Safety, Tolerability, And Pharmacokinetics (PK) Of Multiple Doses Of PF-06865571 In Healthy, Including Overweight And Obese, Adult Subjects
NCT03230383 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I, Multiple Dose Study of PF-04447943 in Healthy Elderly Volunteers
NCT00736528 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase 1 Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Pf-05230907 In Healthy Volunteers
NCT01897142 ·Status: COMPLETED ·Phase: PHASE1
-
Single Dose Study To Compare Pharmacokinietics Of 3 Different Formulations Of PF-04991532 In Healthy Volunteers
NCT01351129 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine (PF-07293893) at Different Dose Levels in Healthy Adults
NCT05907395 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Compare The Pharmacokinetics Of Different Formulations Of PF-04937319 In Healthy Subjects
NCT01513928 ·Status: COMPLETED ·Phase: PHASE1
-
OPEN LABEL, 2-PERIOD STUDY, TO COMPARE BIO-AVAILABILITY OF 2 DIFFERENT FORMULATIONS OF PF-05221304 IN HEALTHY ADULTS
NCT03871439 ·Status: COMPLETED ·Phase: PHASE1
-
A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers
NCT04931147 ·Status: COMPLETED ·Phase: PHASE1
-
Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-04958242 In Healthy Volunteers
NCT02228395 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants
NCT05431153 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn About the Study Medicine Called PF-07258669 in Older Adults Including Those at Risk of Malnutrition
NCT07086664 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Learn How the Study Medicine PF-07899895 Are Tolerated and Act in the Body of Healthy Adults
NCT06137729 ·Status: TERMINATED ·Phase: PHASE1
-
A Study To Look At Safety And Blood Concentrations After Multiple Doses Of PF-03382792 In Healthy Elderly Individuals
NCT01089738 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study To Evaluate The Safety, Tolerability And Plasma Drug Levels Following A Single Dose Of PF-04995274 In Healthy Adult Volunteers
NCT01091272 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults.
NCT06532383 ·Status: COMPLETED ·Phase: PHASE1
-
A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers
NCT01161069 ·Status: COMPLETED ·Phase: PHASE1
-
To Evaluate Safety, Tolerability, Plasma Drug Levels And Other Biological Effects In Healthy Volunteers
NCT01045863 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate the Drug Exposure of Single Ascending Doses of BMS-986369 and the Effect of Food on the BMS-986369 in Healthy Participants
NCT05350800 ·Status: COMPLETED ·Phase: PHASE1
-
Single Dose Study of PF-05230907 in Healthy Japanese Subjects
NCT02537002 ·Status: COMPLETED ·Phase: PHASE1