MedTrace Logo

10-Year Survival After Acute Hip Fracture in Patients With Preclinical/Clinical Alzheimer Pathology

NCT07443566 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 404

Last updated 2026-03-02

No results posted yet for this study

Summary

This study is a 10-year follow-up of a previously enrolled cohort of patients who underwent surgery for acute hip fracture with spinal anesthesia and had pre-fracture cognitive status assessed (Clinical Dementia Rating, CDR) and cerebrospinal fluid (CSF) biomarkers related to Alzheimer's disease measured (e.g., Aβ42/Aβ40 ratio, total tau, phosphorylated tau). The primary aim is to determine long-term survival at 10 years after index hip fracture surgery and to evaluate whether baseline cognitive status and/or Alzheimer-type CSF biomarker profiles are associated with long-term mortality.

Conditions

  • Hip Fractures (ICD-10 72.01-72.2)
  • Alzheimer s Disease
  • Dementia

Sponsors & Collaborators

  • Bengt Nellgård

    lead OTHER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07443566 on ClinicalTrials.gov