Comparison of Root Canal Desinfection Protocols
NCT07439614 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2026-06-23
Summary
Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis
Conditions
- Periapical Periodontitis
Interventions
- DEVICE
-
Desinfection device
Desinfection protocol with (LAI): Er,Cr:YSGG laser (2780 nm) delivered with a radial-firing tip.
- DEVICE
-
Analytical microbiological methods
Endocator: Measures ATP levels (Endoscore and RLU) to rapidly assess bacterial load in less than one minute.
Sponsors & Collaborators
-
State University of New York at Buffalo
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-04-01
- Primary Completion
- 2026-12-31
- Completion
- 2027-06-30
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Comparison of Effectiveness of Disinfectants
NCT06811779 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
NCT05361278 ·Status: COMPLETED ·Phase: NA
-
Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal
NCT06836882 ·Status: RECRUITING ·Phase: NA
-
Efficacy of Adjunctive Antimicrobial Photodynamic Therapy for Residual Pockets in Previously Surgically Treated Teeth
NCT03757260 ·Status: UNKNOWN ·Phase: NA
-
Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy
NCT02520375 ·Status: WITHDRAWN ·Phase: NA
-
Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis
NCT03713567 ·Status: COMPLETED ·Phase: NA
-
Hydrogen Peroxide Fumigation in Dental Office Environment
NCT06100848 ·Status: COMPLETED ·Phase: NA
-
Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous.
NCT03203551 ·Status: COMPLETED ·Phase: NA
-
Guided Biofilm Therapy for Periodontal Patients.
NCT05263622 ·Status: COMPLETED ·Phase: NA
-
Maintaining Oral Health With Bio-products
NCT04033263 ·Status: COMPLETED ·Phase: NA
-
Chlorhexidine-Metronidazole Combination as an Intracanal Medicament on Periodontal Healing
NCT03169946 ·Status: UNKNOWN ·Phase: NA
-
Systemic Probiotics in the Periodontal Treatment
NCT03733379 ·Status: UNKNOWN ·Phase: PHASE3
-
Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection
NCT02126267 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets.
NCT06319261 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Surgical Protocol for Peri-Implantitis Treatment-3
NCT03977324 ·Status: UNKNOWN ·Phase: NA
-
Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization
NCT00707369 ·Status: COMPLETED ·Phase: PHASE4
-
Non-surgical Electrolytic Cleaning Peri-implantitis
NCT05275894 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluation of Bacterial Contamination and Antimicrobial Efficacy on Charcoal-Infused vs, Standard Nylon Toothbrush Bristles.
NCT07365748 ·Status: COMPLETED ·Phase: NA
-
Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
NCT01852253 ·Status: COMPLETED ·Phase: NA
-
Microbial Associations in Periodontal Health and Disease
NCT00066001 ·Status: COMPLETED ·Phase: PHASE2
-
Bacterial Arrangement on the Teeth
NCT01712672 ·Status: COMPLETED
-
Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy
NCT01532674 ·Status: UNKNOWN ·Phase: PHASE4
-
Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study
NCT06860321 ·Status: COMPLETED ·Phase: NA
-
Treatment of Young Permanent Teeth With Different Adjuvant Approaches
NCT05291195 ·Status: COMPLETED ·Phase: NA
-
Predictors of Periodontal Outcomes Post-sanative Therapy
NCT04639661 ·Status: TERMINATED