Non-surgical Electrolytic Cleaning Peri-implantitis

Summary

Electrolytic cleaning is a promising treatment for dental implant decontamination, but this mode of therapy has not yet been clinically tested as an adjunct to the non-surgical treatment of periimplantitis.

A prospective clinical and radiographic case series study will be performed to evaluate the clinical performance of the adjunctive use of electrolytic cleaning as an adjunct to a non-surgical therapy protocol that includes curettage of the peri-implant soft tissue. This is study is a proof of principle study, thus, a case series study is selected to start with. If the results of this case series study are favourable, a future study with a clinical trial design is then planned to do.

Conditions

• Peri-Implantitis

Interventions

BEHAVIORAL

Implant hygiene instructions and removal of the prosthesis

Verbal instructions on implant hygiene practices and removal of the implant supported prosthesis

PROCEDURE

Non-surgical peri-implantitis treatment /microsurgery

Removal of the granulation tissue and mucosa and bone defect curettage with a steel curette 4R/4L (Hu-Friedy, Chicago, IL, USA) after applying local anestesia

PROCEDURE

Implant surface decontamination 1(ultrasonic device)

Removal of supra and submucosal calculus with slim ultrasonic devices (Piezon PS instrument EMS; Nyon, Swiss).

PROCEDURE

Implant surface decontamination 2 (air polishing)

Erythritol air powder-spray system (Air-flow ® master piezon, EMS, Nyon swiss) implant surface treatment. This will be performed by separating the soft tissue with the aim of a periodontal probe (CP 15, Hu-Friedy, Chicago, IL, USA).

PROCEDURE

Implant surface decontamination 3 (electrolytic cleaning)

Electrolytic cleaning of the implant surface following manufacturer's instructions (GalvoSurge Dental AG, Widnau, Switzerland), with the help of a non-metal periodontal probe to separate the soft tissues and aim the implant surface in all its length.

DRUG

Antibiotic treatment (Metronidazole)

Antibiotic treatment (Metronidazole 500 mg, every day/ 7 day).

PROCEDURE

Modification and polishing of the prosthesis

If necessary, modification and polishing of the prosthesis to make it cleanable.

Sponsors & Collaborators

• Universidad Complutense de Madrid

  lead OTHER

Principal Investigators

• Mariano Sanz Alonso · University Complutense Madrid

Study Design

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-10-12

Primary Completion

2024-03-30

Completion

2024-12-30

Countries

• Spain

Study Locations