Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring

NCT07435857 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 221

Last updated 2026-02-27

No results posted yet for this study

Summary

The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.

Conditions

  • Metabolic Health

Interventions

BEHAVIORAL

exercise

The present study is a prospective follow-up of a randomized controlled trial (RCT) that was conducted in the Department of Obstetrics and Gynecology, Peking University First Hospital, from December 2014 to April 2017. In this RCT, 300 obese/overweight pregnant women (prepregnancy BMI ≥24 kg/m²) at \<12+6 weeks of gestation were randomized to exercise (n=150) and control groups (n=150), and the efficacy of regular exercise in early pregnancy to prevent GDM among overweight/obese pregnant Chinese women was investigated. The patients allocated to the exercise group were assigned to a cycling program (3 times per week, at least 30 min/session, rating of perceived exertion 12-14); the program was initiated within 3 days of randomization and continued until 37 weeks of gestation. The patients in the control group maintained their usual daily activities. The original RCT has been reported previously (Wang, C.Am. J. Obstet. Gynecol. 2017, 216 (4), 340-351.)

Sponsors & Collaborators

  • Peking University First Hospital

    lead OTHER

Principal Investigators

  • Chen Wang · Peking University Frist hospital

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-01
Primary Completion
2024-11-15
Completion
2024-11-15

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07435857 on ClinicalTrials.gov