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Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste

NCT07428603 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 118

Last updated 2026-02-24

No results posted yet for this study

Summary

This randomized, examiner-blind, parallel-group clinical study evaluated the effectiveness of a whitening toothpaste compared with a control toothpaste in removing extrinsic tooth stain over six weeks of twice-daily unsupervised use. Adult subjects were assessed at baseline and after 7, 14, 28, and 42 days of product use using the Macpherson Modification of the Lobene Stain Index. Oral soft and hard tissues and subject-reported sensory responses were also evaluated throughout the study.

Conditions

  • Stain Removal Efficacy

Interventions

OTHER

Whitening Test Dentifrice (Code 826)

Whitening toothpaste used twice daily for two minutes per brushing for six weeks.

OTHER

Control dentifrice (Code 378)

Non-whitening toothpaste used twice daily for two minutes per brushing for six weeks.

Sponsors & Collaborators

  • Church & Dwight Company, Inc.

    lead INDUSTRY

Principal Investigators

  • Annahita Ghassemi, PhD · Church & Dwight, Inc.

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-08
Primary Completion
2024-09-20
Completion
2024-09-20

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07428603 on ClinicalTrials.gov