MedTrace Logo

The Effect of Exercise-Induced Irisin on Brain Function and Postoperative Delirium in Older Adults

NCT07424170 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2026-03-10

No results posted yet for this study

Summary

The goal of this observational study is to learn how exercise-induced irisin protects the brain. It also explores irisin's effect on postoperative delirium (POD) in older adults. The main questions it aims to answer are:

Does daily activity link to POD? Does irisin play a mediating role in this process? Researchers will enroll active and inactive adults aged 65 and older. All will have surgery under spinal anesthesia. The researchers will measure irisin levels in spinal fluid. They will track POD and other complications for five days after surgery.

Conditions

  • Post Operative Delirium

Interventions

BEHAVIORAL

Preoperative physical activity level

Before the surgery, the activity levels of the participants over the past week were assessed using the Physical Activity Scale for the Elderly (PASE).

Sponsors & Collaborators

  • Peking University People's Hospital

    lead OTHER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-15
Primary Completion
2026-12-26
Completion
2026-12-31

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07424170 on ClinicalTrials.gov