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The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity

NCT07423065 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-04-28

No results posted yet for this study

Summary

This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with prediabetes and overweight or obesity (BMI ≥ 27 kg/m²). Thirty participants will undergo both open and blinded CGM phases, separated by a washout period. The study aims to assess whether access to real-time glucose data promotes behavioral change and improves metabolic health compared with blinded CGM use.

Conditions

  • Pre Diabetic
  • Obesity & Overweight

Interventions

DEVICE

Continuous Glucose Monitoring (CGM)

Use of a continuous glucose monitoring system to measure interstitial glucose levels. During the open CGM phase, participants have real-time access to glucose data; during the blinded CGM phase, glucose data are masked from participants.

Sponsors & Collaborators

  • Diabetes Outpatient Clinic, Community Health Center Koper, Slovenia

    collaborator UNKNOWN

  • University Medical Centre Ljubljana

    collaborator OTHER

  • University of Primorska

    lead OTHER

Principal Investigators

  • Ajda Urbas, MD · Diabetes Outpatient Clinic, Community Health Center Koper, Slovenia

  • Mojca Jensterle Sever, PhD · University Medical Centre Ljubljana, Department Of endocrinology and diabetes, Medical Faculty, University of Ljubljana

  • Zala Jenko Pražnikar, PhD · University of Primorska, Faculty of Health Sciences

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2027-04-01
Completion
2027-09-01

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07423065 on ClinicalTrials.gov