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Flexible Bronchoscopy in Resistant Pneumonia in PICU

NCT07421440 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 58

Last updated 2026-02-19

No results posted yet for this study

Summary

Pneumonia is one of the most common and serious infections in children, especially those admitted to Pediatric Intensive Care Units (PICUs). Some children do not improve after at least five days of appropriate broad-spectrum antibiotic treatment. This condition is known as resistant or non-resolving pneumonia.

Flexible fiberoptic bronchoscopy (FFB) is a procedure that allows doctors to directly examine the airways and collect samples from the lungs for laboratory testing. This study aims to evaluate the role and usefulness of flexible bronchoscopy and bronchoalveolar lavage (BAL) in identifying the causes of resistant pneumonia in critically ill children.

The study will include children admitted to the PICU at Abu El-Reesh Children's Hospital, Cairo University, who show no clinical or radiological improvement after five days of first-line antibiotic therapy. The results of this study may help improve diagnosis, guide targeted treatment, and enhance outcomes in children with resistant pneumonia.

Conditions

Sponsors & Collaborators

  • Mansour Gomaa Mohammed Saleh

    lead OTHER

Eligibility

Min Age
3 Months
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-05
Primary Completion
2026-04-01
Completion
2026-04-30

Countries

  • Egypt

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07421440 on ClinicalTrials.gov