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Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis

NCT07407491 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 172

Last updated 2026-02-12

No results posted yet for this study

Summary

Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis compared with standard systemic antibiotic therapy alone?

Conditions

  • Acute Cholangitis
  • Biliary Tract Infection
  • Biliary Obstruction
  • Choledocholithiasis
  • Malignant Biliary Stricture

Interventions

DRUG

Gentamicin - single dose

Administration described in arm/group description

DRUG

Distilled water

Administration described in arm/group description

Sponsors & Collaborators

  • National University of Malaysia

    lead OTHER

Principal Investigators

  • Azlanudin Azman · Universiti Kebangsaan Malaysia Medical Centre

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-07-09
Primary Completion
2026-07-08
Completion
2026-07-08

Countries

  • Malaysia

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07407491 on ClinicalTrials.gov