Development of a Novel Algorithm for Real-Time Bedside Assessment of Insulin Resistance in Critically Ill Patients Based on Continuous Glucose Monitoring Data
NCT07385391 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 179
Last updated 2026-02-04
Summary
This study aims to develop and validate a novel algorithm for the real-time assessment of insulin resistance in critically ill patients using Continuous Glucose Monitoring (CGM). Current methods for assessing insulin resistance are often invasive or unfeasible in the intensive care setting. By analyzing the dynamic correlation between CGM readings and reference blood glucose fluctuations, the investigators seek to construct a new algorithmic metric. The study will further evaluate the association of this new metric with established insulin resistance indices, organ function, and patient clinical outcomes.
Conditions
- Critical Illness
- Metabolism Disorders
- Insulin Resistance
Sponsors & Collaborators
-
Chinese Medical Association
lead NETWORK
Principal Investigators
-
Wenkui Yu, PhD, Professor · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-13
- Primary Completion
- 2024-03-13
- Completion
- 2025-10-01
Countries
- China
Study Locations
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