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GastroFlow: Investigation of the Gastrointestinal Blood Flow in Patients With Postprandial Hypotension

NCT07381816 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-02-02

No results posted yet for this study

Summary

This project will describe the mechanisms of action and the relative contributions of GIP to changes in gastrointestinal blood flow induced by oral glucose and endogenous GIP with the use of a receptor antagonists GIP(3-30)NH2 in patients with postprandial hypotension.

Conditions

  • Postprandial Hypotension
  • Healthy
  • Blood Flow

Interventions

OTHER

MRI + GIPR antagonist (Tool)

GIP(3-30)NH2 infusion, oral glucose during MRI scans

OTHER

MRI + hangrip

Hangrip exercises, oral glucose during MRI scans

OTHER

Saline and oral glucose

Saline infusion oral glucose during MRI scans

Sponsors & Collaborators

  • Rigshospitalet, Denmark

    collaborator OTHER

  • University of Copenhagen

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-15
Primary Completion
2026-12-01
Completion
2027-05-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07381816 on ClinicalTrials.gov