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A New Classification System for Lymph Nodes in Colon Cancer: The Prognostic Significance of the Anatomical Distribution of Metastatic Lymph Nodes and the Number of Tumor Deposits

NCT07380464 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2026-02-02

No results posted yet for this study

Summary

This study aims to investigate the prognostic significance of LNM distribution and establish a new classification system integrating both nodal quantity and anatomical location.The main question it aims to answer is:

Does the new N staging based on lymph node metastasis patterns and cancer nodules provide a more accurate prediction of the prognosis of colon cancer patients compared to the AJCC N staging? The relevant clinical characteristics, treatment processes, postoperative pathological data and post-discharge prognosis information of the enrolled patients were collected through the follow-up offices and the medical record system. The data were analyzed. The main research endpoints were: overall survival (the time between the initial surgery and death or the last follow-up); disease-free survival (the time between the initial surgery and disease metastasis, recurrence or death).

Conditions

  • Colon Cancer
  • Tumor Deposits
  • Lymph Node Metastases
  • TNM Staging

Sponsors & Collaborators

  • Cai Zerong

    lead OTHER

Principal Investigators

  • Zerong Cai, MD · Sixth Affiliated Hospital, Sun Yat-sen University

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-03-05
Primary Completion
2025-07-31
Completion
2025-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07380464 on ClinicalTrials.gov