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Haematococcus Pluvialis Astaxanthin for Brain Aging

NCT07379437 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-01-30

No results posted yet for this study

Summary

We recruit community-dwelling older adults aged 50 and above for a 6-month intervention. Participants are divided into three groups:

Placebo Group, Low-Dose Group ( 6 mg/d Haematococcus pluvialis Astaxanthin), High-Dose Group (12 mg/d Haematococcus pluvialis Astaxanthin).

Peripheral blood samples and Other tests are collected at baseline, 3 months, and 6 months to measure mitochondrial function and oxidative stress levels.

Assessments include: 1.Cognitive \& Neurophysiological Assessment: Using the MoCA (Montreal Cognitive Assessmentscale) and ERP (specifically P300) monitoring. 2.Brain Imaging: MRI (Magnetic resonance imaging) is used to analyze changes in brain function. 3.Metabolomics: A series of laboratory techniques are used to analyze routine metabolic indices, plasma astaxanthin, mitochondrial function, oxidative stress markers, and cognition-related neurobiomarkers.

Conditions

  • Brain Aging

Interventions

DIETARY_SUPPLEMENT

Low-Dose AST

Low-Dose AST Group:6 mg/d Astaxanthin (Haematococcus pluvialis)

DIETARY_SUPPLEMENT

High-Dose AST

High-Dose Group: 12 mg/d Astaxanthin (Haematococcus pluvialis)

OTHER

Placebo

Placebo

Sponsors & Collaborators

  • Capital Medical University

    lead OTHER

Principal Investigators

  • Linhong Yuan, Doctor · Capital Medical University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2026-12-01
Completion
2027-02-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07379437 on ClinicalTrials.gov