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Treatment Strategy to Enhance Nrf2 Signaling in Older Adults

NCT04848792 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2025-08-28

No results posted yet for this study

Summary

Exercise is the cornerstone of disease prevention and often an important component of treatment. However, the efficacy of an exercise stimulus is reduced with aging. This study will investigate whether adding a treatment with phytonutrients found in cruciferous vegetables can improve the exercise response in older individuals.

Conditions

  • Aging Problems

Interventions

DIETARY_SUPPLEMENT

Sulforaphane

Myrosinase-active whole broccoli sprout material

DIETARY_SUPPLEMENT

Placebo capsules

Placebo capsules

Sponsors & Collaborators

  • Villanova University

    collaborator OTHER

  • Northern Arizona University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-09
Primary Completion
2025-05-27
Completion
2025-05-27

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04848792 on ClinicalTrials.gov